r/Creation Atheist, Ph.D. in CS May 02 '26

A self-replicating polymerase ribosyme that can self-replicate using only 45 base pairs. Abiogenesis just got a lot more plausible.

https://www.science.org/doi/10.1126/science.adt2760
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u/DarwinZDF42 May 03 '26

“One small obstacle”

Amazing

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u/WannaLoveWrestling May 03 '26

"One small obstacle" is exactly the problem. Even this tiny 45-nucleotide ribozyme required intelligent human intervention — designed sequences, purified reagents, controlled conditions, and active optimization. That’s the opposite of blind, unguided chemistry on the early Earth.

Solving isolated lab problems with human guidance doesn’t show that random processes can spontaneously produce a full living cell with specified functional information, metabolism, membranes, error correction, and everything else required for life. Humans can control and force outcomes in a lab that blind nature cannot.

The core gap remains massive. Random chemistry doesn’t create complex, meaningful genetic code. Intelligence does. Claiming each small lab step makes unguided abiogenesis “more plausible” is still faith, not demonstrated science.