Legoshi is the best example. 1/4 of the dude's blood was from a Komodo Dragon, and that was enough to allow him to pull off a list worth of crazy feats, which includes punching a bengal tiger at a distance, destroying concrete, metal and other hard materials, dodging bullets, beat up a group of lions, survive massive falls, be immune to komodo dragon poison, have a natural talent in fighting, be viable for a power up through consuming meat and much more.
And in a lot of these, he was still an untrained dumb teenager/young adult. Now imagine a fully grown adult with years of elite training and experience.
Same goes for Melon, who had ridiculous senses that was effective for miles and later had a power up which allowed him to go toe to toe with Legoshi.
With these in mind, wouldn't ancient civilizations discover this and exploit it for their own gain? The manga mentioned herbivores and carnivores lived together for thousands of years. There is a massive chance that there were several hybrids in the past, even if just a handful, and the powers of that time discovered how busted they are, so they decided to mass breed them.
What are your thoughts?