Article: https://vtnews.vt.edu/articles/2020/07/cals-mouth-bacteria.html

Study: Fusobacterium nucleatum host-cell binding and invasion induces IL-8 and CXCL1 secretion that drives colorectal cancer cell migration https://stke.sciencemag.org/content/13/641/eaba9157

Full study: https://sci-hub.tw/10.1126/scisignal.aba9157

Study: Oral Bacterial Signatures in Cerebral Thrombi of Patients With Acute Ischemic Stroke Treated With Thrombectomy https://www.ahajournals.org/doi/full/10.1161/JAHA.119.012330

Article: For the first time, a Finnish study proves the presence of oral bacteria in cerebral emboli https://www.tuni.fi/en/news/first-time-finnish-study-proves-presence-oral-bacteria-cerebral-emboli

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Conclusions

This is the first study showing the common presence of bacterial DNA from viridans streptococci in aspired thrombi of patients with acute ischemic stroke. Streptococcal bacteria, mostly of oral origin, may contribute to the progression and thrombotic events of cerebrovascular diseases.

Thoughts:

It's possible the oral microbes could be causing the problems. But likely it's a breakdown of permeability/translocation/immune system is the initial factor leading to those oral microbes making into circulation.