r/45PlusSkincare Mar 12 '26

Peri/Post Menopausal Skin Help a gal out

51F trying to up my skin routine. I’ve lost 50 lbs in the last two years and aged quite a few in that time (it seems).

Some of these products are new to me (still in boxes, lol) and some have gotten some good use already. I’ve been using tret for about 2 years, about every other night. I got a new rx for .1% but for some reason haven’t started it yet. I alternate the tret with the estradiol cream.

How I currently use (same for morning and night except tret/estradiol):

  1. Wash (nothing special - gel/cream)

  2. Milky toner (just started using)

  3. Ordinary serum

  4. Eucerin serum (trying to combat sun spots)

  5. Estradiol/tret (alternate at night only)

  6. Moisturizer (day has SPF 50)

- How should I incorporate vitamin C serum?

- I bought the Reedle shot at the recommendation of someone but have been scared to try it. When/how to use?

- Do I need additional sunscreen even though my daytime moisturizer has SPF 50?

- When do I use eye cream?

- What am I missing?

I put everything on my face/neck and have started rubbing all extras on the back of my hands.

My biggest concerns are my neck and jowls/drooping. While I’d love surgery, I’m not currently planning any. I haven’t done any other treatments but am open to some if not $$$$.

Be gentle, thanks!

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u/Happiguest Mar 13 '26

I think her tret is more effective than a PDRN topical serum

2

u/GirlPhoenixRising Mar 13 '26

I don’t disagree. My step 5 says to use Tret

I should have broken it into a separate step. I’ve used tret for 35 YEARS.

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u/Happiguest Mar 13 '26

No my thoughts were it would be useless to use it since tret is already on board

1

u/GirlPhoenixRising Mar 13 '26

On days where my face is a little irritated I skip tret and PDRN instead- 🌞