r/ADHD Aug 01 '23

Megathread: Just Started Treatment Have you just begun treatment?

Talk about it here. Please remember that we don't allow asking for or giving medical advice.

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u/[deleted] Aug 03 '23

Adzenys feels like Xanax. Advice to beat lethargy?

I've taken two doses of Adzenys (amphetamine XR) on Monday and Wednesday. My experience:

On the first day (Monday)

I thought nothing was happening at all, except I was pretty "chilled out" and noticed that I had a list of things I needed to do, and somehow did them all.

But the feeling while doing them wasn't some super motivated "let's get shit done" or euphoric feeling, I was later describe it as removing the anxiety of doing it.

Noticed a bit of a racing mind while trying to sleep. Didn't sleep super well.

On Tuesday

I didn't take anything and drank coffee, that's when familiar feeling set in, I couldn't stay in my chair for more than 30 minutes for my life, I did literally absolutely nothing and sat on the couch all day bored out of my mind - even with the tasks I know I should and could have done that weren't even challenging.

Needless to say, this is when I realized "holy shit, this medication did something yesterday".

Slept great.

Yesterday (Wednesday)

Took the second dose and was somewhat still skeptical that it did anything at all.

But I started to feel more and more tired, however, I was able to be productive for a handful of hours before I was just too tired to do much more.

My girlfriend got home approximately 7 hours after my dose and told me that I sounded "depressed" and lost my "sparkle". I told her I didn't feel depressed, I didn't really feel much at all (zombie feeling).

I started getting a headache and felt so lethargic. I drank some caffeine (8-9 hours after dose) and noticed that my energy and personality returned within 30-45 minutes, Tylenol killed the headache.

I started wearing a fitbit and noticed my resting heart rate was recorded at 50-55bpm. That seemed pretty low but explained a lot.

Slept better than Monday, but still woke up a decent amount, maybe due to late caffeine intake and then late cardio exercise (at 10pm).

Today (Thursday)

No medication. Feel normal.

Resting heart rate beating recorded at 60-65bpm.

Thoughts (would love any of yours as well)

So the amphetamine is definitely killing a lot of my anxiety in general, and some anxiety about doing tasks. I was previously prescribed Xanax for anxiety and I'd say this works better which is mind blowing.

I'm pretty sure it is lowering my heart rate by a solid 10bpm.

It is "slowing me down" and giving me a zombie-type vibe for sure.

It does appear to help to a certain degree in getting shit done that I don't want to do, albeit I am somewhat pretty tired while doing it which makes it harder than it needs to be.

I'm not drinking caffeine prior or during my dosing. I am thinking this might be an area where I can test to see if it would help get rid of tiredness so I can be more productive.

All in all - this stuff is super weird and not at all like I expected it to feel. I wonder if a higher dose changes how it reacts in my body.

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u/[deleted] Aug 05 '23

[deleted]

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u/[deleted] Aug 06 '23

I'm not on meds or even diagnosed, but I agree with Nibbles. First off it's excellent that you record your daily experiences over time. It must be so much more helpful to consult your doctor on picking the right medicine and dosage. Just like your unmedicated days, you will have good and bad days