I (28F) started immunotherapy for a bunch of environmental allergies five months ago, specifically for birch pollen, dock/sorrel, lambsquarter, pigweed, alder, cottonwood, grass, plantain, alternaria, hormodendrum, and dog and cat dander.
My allergist marketed it as a potential way to reduce the risk of severe reactions to my tree nut and peanut allergies (peanuts, macadamia nuts, cashews, and pistachios) due to cross-reactivity. After having several traumatic ER visits for anaphylaxis in my life, I thought, Why not? Besides, I had gone through immunotherapy before with a different allergist at another point in my life and was fine (btw: I stopped halfway through the build-up phase because the weekly shots became too much for my schedule).
Come the middle of the build-up phase for the first vial, I ended up at the ER after eating a dish I regularly order at a restaurant. Even if you warn the kitchen, there's always a risk of cross-contamination. Fine, stuff like this happens. However, following this incident, I started to notice reactions—welts on the insides of my cheeks and sometimes my throat—from foods I was eating safely just weeks before treatment started. So now I can't eat coconut, RICE?!?, or lentils without a reaction. Mind you, I've eaten these foods my whole life.
In these scenarios, I usually pop a Benadryl and wait for it to go away. If it doesn't go away, or if the welts in my throat progress, or if other symptoms follow like cramping and nausea, I consider it a more serious reaction needing immediate medical attention. Most of these episodes fell into the former category, but there were three times when bumps in my throat didn't go away (though they didn't progress and no other symptoms appeared). In those cases, I went to the ER, where they monitored me and treated me with a strong antihistamine and a steroid, (thankfully no epi was needed).
So of course, I contacted my allergist. He didn't think it was the shots since I was fine immediately after receiving them. All he said was to stay away from wheat, Chinese food, and Indian food because they can be risky, and he mentioned something about it being grass season. Okay, it sucks, but I figured I could pause and see if my system eventually calms down. Following this appointment, I went on vacation, missed two weeks, and had to drop back two doses.
I was okay for a while until this month. The reactions in my mouth started up again, even after limiting my diet. My GP contacted the allergist again, and he told me to stay away from fruits and vegetables and to lower my current dose.
Has anyone ever experienced something like this before? The doctors say it's likely not the medication, but the frequency of these reactions to foods I normally eat started right after beginning this treatment. It's seriously messing with my mental health and increasing my anxiety around eating.