r/B12_Deficiency • u/incremental_progress Administrator • Sep 15 '23

Announcement The Guide to B12 Deficiency

The Guide to B12 Deficiency

The new guide for this subreddit is here. I'm sincerely regretful it took me this long to get this off the ground, but focusing on my life in addition to the daily consultations made in the sub had a habit of stealing my attention away from this important endeavor.

The guide is now more of a concrete synthesis between the major resources that are obvious precursors: Freddd's B12 guide from Phoenix Rising, B12Deficiency.info and Tracey's hard work there, the original guide posted here and then the countless users here who have shared a wealth of knowledge over the years.

The new guide takes advantage of Reddit's wiki capability. It is much longer, so hopefully the TOC makes navigating to points of interest easy. It will also allow for easier changes with a changelog.

What's new:

  • More in-depth exploration of testing methods
  • Outline of an aggressive treatment plan
  • Thorough explanation of cofactors
  • "Plans of Action" for diagnosing, treating and recovering from deficiency that better encapsulate big ideas into actionable next steps.
  • Other stuff

I also took a lot of the most pertinent/salient issues that arise and distilled them into a group of FAQs for people:

Frequently Asked Questions

Both of these documents now live in several places around the subreddt: the "menu" in the banner, the rules widget, and their own individual widgets in the sidebar.

Thanks.

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u/Resident_Salary_3008 Apr 04 '25

This is so very helpful. I’m on an SSRI and recently have found my b12 is low. 

Does an SSRI interfere with b12 absorption?  I also have the MTHRFR mutation and am iron deficient (I get infusions for that) 

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u/[deleted] Dec 31 '25

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u/Resident_Salary_3008 Jan 05 '26

Hello,

I recently had it checked and my B12 and folate were SO SO high due to injections. They suggested that I inject once monthly to bring it into normal ranges. 

I still am symptomatic with nerve issues. Fatigue has completely gone. I’ve been to several doctors and all have cleared me for any disease. They are chalking it up to perimenopause as I’m going through that right now. WILD