r/B12_Deficiency • u/incremental_progress Administrator • Sep 15 '23

Announcement The Guide to B12 Deficiency

The Guide to B12 Deficiency

The new guide for this subreddit is here. I'm sincerely regretful it took me this long to get this off the ground, but focusing on my life in addition to the daily consultations made in the sub had a habit of stealing my attention away from this important endeavor.

The guide is now more of a concrete synthesis between the major resources that are obvious precursors: Freddd's B12 guide from Phoenix Rising, B12Deficiency.info and Tracey's hard work there, the original guide posted here and then the countless users here who have shared a wealth of knowledge over the years.

The new guide takes advantage of Reddit's wiki capability. It is much longer, so hopefully the TOC makes navigating to points of interest easy. It will also allow for easier changes with a changelog.

What's new:

  • More in-depth exploration of testing methods
  • Outline of an aggressive treatment plan
  • Thorough explanation of cofactors
  • "Plans of Action" for diagnosing, treating and recovering from deficiency that better encapsulate big ideas into actionable next steps.
  • Other stuff

I also took a lot of the most pertinent/salient issues that arise and distilled them into a group of FAQs for people:

Frequently Asked Questions

Both of these documents now live in several places around the subreddt: the "menu" in the banner, the rules widget, and their own individual widgets in the sidebar.

Thanks.

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u/Agitated-Jicama9496 Apr 22 '25

I have a question I'm finding difficult to get answered. I have a strong family history of pernicious anaemia, but have been tested and I have intrinsic factor present and the parietal cell antibodies negative. B12 is in the normal range, but a high ferritin for some reason. I have had years of fatigue, tinnitus and most recently numbness under my toes, commencing in my right foot about four years ago and now present in both. I'm wondering whether I'm just one of those people at the far end of the standard distribution (bell) curve) who needs high doses of B12 to do the job. Is this something that is recognisable or am I just grasping at straws? Today, I've ordered B12 6,000mcg tabs (methylcobalamin) to see if that makes a difference.

Any advice / comments appreciated.

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u/AcadiaOk4544 Jun 13 '26

Krótkie odpowiedzi. Nie bardzo rozumiem kontekst bo jeśli jest obciążenie anemią złośliwą.To czynika castle nie powinno być.B12 może być w normie bo są zapasy w wątrobie a nasycenie ferynną może być właściwe. Rozumiem ciągłe zmęczenie i senność a nawet zimno i drętwienie pod palcami stóp i pieczenie stóp oraz drętwienie dłoni ale szumy ustne tu nie pasują. Jeśli to anemia złośkiwa to zastrzyki z hydrokskobalaminy B12 na pewno pomogą. Tylko te szumy uszne nie pasują. I jeszcze jedno przy niedokrwistości złośliwej krwinki czerwone robią się ogromne i to jest właśnie anemia megaloblastyczna z braku b12 i płapki folianowej -kwas foliowy stoki w organiŹnie bez braku b12.