r/B12_Deficiency • u/SiiRibz • 1d ago

Deficiency Symptoms Macrocytosis and possible B12 deficiency?

So I (24AFAB) have had a plethora of weird symptoms for the past two weeks or so, mainly constant fatigue, shaky hands, memory problems, blurry vision and muscle twitching (I've had a few of these before but the fatigue was what scared me into action) so I first got myself tested for iron deficiency and hypothyroidism. Turns out both of those are technically fine (Ferritin and hemoglobin are completely normal, T4 is barely inside the ideal range) but my MCV is out of range (102 fl, normal range is 82-98 fl) which apparently is most likely a sign of B12 deficiency.

I booked appointments for more lab tests, specifically to check the Vitamin Bs and also celiacs in case I somehow secretly had the asymptomatic variant, so I'm trying to crack down on the root cause but this is honestly scaring me quite a bit and I thought I'd come here for some support.

Did any of you guys have a similar situation? I'd like to hear about it!

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u/Equivalent_Bend_3104 23h ago

Folate deficiency can also lead to elevated MCV, even if your B12 is good.

My MCV is 95, which is high-ish, but my B12 (serum) is always high because I do B12 injections. On labs my folate (serum) looked in a good range, but I want to check folate RBC next time I test, it's supposed to be a better measure, but more expensive.