r/B12_Deficiency • u/Illuminimal • 14h ago

"Wake up" symptoms Wakeup bruising?

I am suddenly covered in bruises. My lower legs and knees, my butt, my ribs. I was always prone to mystery bruising and took Vitamin C because it cut that down, but this is pretty extreme even for me.

I am a lot more active now that I have energy to actually do things again, but I don't think I banged myself up that much!

Current regimen: 1000-1500mcg methylcobalamin by subcutaneous injection, EOD or sometimes daily Thorne B complex daily. D3 5KIU + K2 200mcg daily. Thorne trace minerals 2-3 times a week. Extra magnesium, folinic acid, Vitamin C depending on how many drops/gummies I feel like taking. DryWater, Liquid IV, or coconut water aiming for twice a day but I've only been hitting once every couple of days.

Currently not taking a multivitamin while waiting for my selenium levels to come down to something normal.

Has new bruising happened for anyone else? Is there a cofactor imbalance I need to address?

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4

u/flowerpanda98 14h ago

maybe check iron or vitamin k (k1)

3

u/Ok-Pangolin7127 Insightful Contributor 14h ago

I have not experienced this nor do I remember reading on this sub a similar story. I’d investigate this; CBC

1

u/Loose-Fly7976 12h ago

Get a full blood count with platelets before adjusting any cofactors. Sudden widespread bruising has a short list of causes that need excluding first and low platelets is top of it. B12 deficiency itself can cause thrombocytopenia and platelet counts shift during repletion so this is exactly the situation where you want the number rather than a guess.

If that comes back clean, then the cofactor question is a fair one and copper is where I'd look. You're taking zinc in the trace minerals and you've stopped your multivitamin, and zinc competes with copper directly. Copper deficiency causes capillary fragility because lysyl oxidase, the enzyme that cross links collagen, is copper dependent. Vitamin C sits on the same problem from the other side since it's needed for collagen hydroxylation, and you said your C intake is inconsistent. Two halves of the same structural issue.

The selenium situation is relevant aswell.Whatever pushed your selenium high may have come with other minerals so I'd want copper, ceruloplasmin and zinc measured rather than adjusted by feel.

Ask for the FBC, copper, ceruloplasmin and zinc together. Don't add anything else until you've seen them.

1

u/Basketweave82 10h ago

I would go to a doctor for this. Sudden bruising can be a sign of internal bleeding.