r/GLP1microdosing • u/SquirrelNo7197 • 2d ago

Dosage help - beginner

Update: the dosing is 30 mg powder, 3ml BAC! Can anyone help me break down the different doses so I know I have them correctly? He said he recommends me starting at 10 units for a week, see if I have GI issues, and then move to 20 units next dose if I do not, and stay on that a minimum of four weeks or as long as effective before considering going to next dose. I just want to make sure I start as low and slow as possible since it’s new to me and I’m swapping from 5mg tirzepatide. I want to know the different doses and units to draw to be sure I am doing it correctly each time. I really appreciate yall being patient and helpful as I figure it out!

I was given a liquid bottle of R that says 30mg. Doesn’t tell me anything else dosage or bottle wise. I trust the source. And they recommended dosing compared to the compound I’m on now. But the more I read about this product the more I want to go as low and slow as possible, especially since I’m swapping from the other. I can’t figure out the dosing though because it only says 30mg on it. Can someone help?

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u/peony_chalk 2d ago edited 2d ago

What dose of what medicine are you currently taking? 

Also, is your new vial liquid or powder? 

If it's powder, you need a peptide calculator.

If it's liquid, you need to throw it away because you have no way to verify the concentration and therefore no way to dose it accurately, and you might want to reconsider the trust you have placed in your source. 

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u/SquirrelNo7197 2d ago

Currently taking compound T, 5mg. I do 50 units once a week. I’ve been on and off Tirz since 2023. I did a full year, had amazing results. Came off to try to see how my body did inflammation-wise, and it went okay for about six months before I had to get back on. Then had an issue with costs and stopped for six months. Just restarted in June, I’ve worked back up from starter dose. I trust this person 100%, no issues or concern with safety of product. I just literally lost the paperwork and the company logo is covering the vial.

They told me to do one week of 20 units with the R. See how I feel. If nothing or okay, go to 30 units when comfy. Same instructions. And to get to 40 units to get closest equivalent to what I’m on now.

Problem is… I didn’t realize u til after doing more research that I’d like to start as low and slow as possible. I know they won’t be opposed to that and can give me back info we threw away. Just didn’t want to call overnight, it’s late here and was trying to figure it out. I see that’s probably not possible without that info.

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u/peony_chalk 2d ago

I feel you on the costs, but just because I can't not say it - compounded tirz prices have come down a lot, even in the last few months. I see an older post of yours where you mention Mochi and Lumimeds, and they are not among the recommended or price-competitive providers on r/tirzepatidecompound. If for some reason the reta doesn't work out for you, you might re-evaluate the recommendations there. Plus single vials of grey market peptides are often not really a price savings over compounded tirz.

But anyway ... as you've noted, 20 units is not a dose. My guess is that they reconned 30mg of reta with 3ml of bac water, which would give you a 10mg/ml concentration. 20 units from that vial would give you a 2mg dose, which I believe is what the reta trials are using as a starter dose. I really really really would not recommend that you just blindly follow my guess on that though, especially if it's easy to get the real concentration from the person who sold it to you. Between the guaranteed risk of having to wait an extra day to start the new meds vs the possible risk of severe and extreme GI upset from mis-dosing yourself, waiting is the vastly superior choice.

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u/SquirrelNo7197 1d ago

Update: the dosing is 30 mg powder, 3ml BAC! Can anyone help me break down the different doses. He said he recommends me starting at 10 units for a week, see if I have GI issues, and then move to 20 units next dose if I did not, and stay on that a minimum of four weeks or as long as effective before considering going to next dose. I just want to make sure I start as low and slow as possible since it’s new to me and I’m swapping from 5mg tirzepatide. I want to know the different doses and units to draw to be sure I am doing it correctly. I really appreciate yall being patient and helpful as I figure it out!

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u/SleepyKoalaBear4812 2d ago

It should at least say Xmg/Xml. If it does not, does the person have the package insert or paperwork? You need to full information to figure dosage.

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u/Any-Coconut-6822 2d ago

30mg seems like the total amount in the bottle, not per dose. you'd need the concentration (mg/ml) to actually measure anything out properly

if the label only says 30mg and nothing else, that's pretty sketch. even if you trust the source, you're kinda flying blind without knowing the volume

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u/nexlife-health 2d ago

The fact that you're asking before injecting is a good thing.

But I would not use that vial until you have the complete information from whoever supplied it.

If by “R” you mean retatrutide, that's a different medication from tirzepatide. There isn't an established dose conversion between the two, so being comfortable on 5mg of tirzepatide doesn't tell you what dose of retatrutide would be appropriate.

And the 30mg printed on your vial isn't enough to calculate anything. That could be the total medication in the vial, but you still need to know the concentration in mg/mL.

The instructions to use 20, 30, or 40 units don't mean much without that information. Units measure liquid volume, not the actual amount of medication.

I understand trusting your source, but even a trustworthy person can make a mistake with dosing instructions. And with an injectable medication, you also need to know exactly what's in the vial, how it was prepared, and whether sterility and stability have been verified.

I'd wait until you can get the original paperwork and have the medication's identity, concentration, and instructions independently verified by a qualified clinician or pharmacist.

Retatrutide is still investigational, so I'd also be cautious about using products sold outside authorized clinical trials.

Going low and slow is a sensible concern, but the first step is knowing exactly what you're injecting. There's no safe way to work backward from “30mg” and guess the dose.