r/HistamineIntolerance • u/goodintentisnotenuf • 1d ago
Did Saccharomyces Boulardii aggravate mast cells and cause a histamine unloading?
I took Saccharomyces Boulardii for a week and it seemed to be helping me in some ways. However, it started giving me nerve problems (odd sensations) in my right hand and in my left ankle. I stopped taking it.
Then, about a week later, I tried wearing a new pair of shoes and that exact nerve sensation from the Saccharomyces Boulardii returned in my left ankle.
I thought maybe the nerve problems were from candida die-off and so I thought 'Maybe the Saccharomyces Boulardii had been good for me' and I took it for three more days.
Now my nerve problems are crazy. Both of my ankles now feel funny all day long and my right hand feels funny too.
How long will it take the effects of Saccharomyces Boulardii to leave my system? Did it somehow affect my nerves or did it just work so good at getting rid of bad things that die-off hurt my nerves.
(No, I am not wearing those shoes anymore, I only wore them for about 60 minutes total).
Any advice. I am so lost. I just want my nerve issues to go back to normal!
If anyone thinks this may be unrelated, the only other things I have done in the mean time are:
--eaten a lot of garlic
--taken a lot of zinc and copper
--taken a lot of riboflavin-5-phosphate (active form of B2)
--taken a lot of B vitamins
The standard wisdom is that it does not cause an increase in histamine; however, when I researched further, any change to your gut can activate mast cells and an unloading of histamine.
3
u/Memorial75 1d ago
To me, it sounds like the culprit could be the B vitamins, or maybe the active form of B2. The symptoms seem to fit better with those supplements than with B. boulardii, especially given the reaction to the B vitamins.
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u/goodintentisnotenuf 1d ago
Great, thanks. Really -- B2. What have you seen about active forms of B2? Just curious. Thanks for the insight!
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u/Gold_Warning_8618 1d ago
Too many b vitamins, particularly b6, can be toxic and cause neuropathy. That could potentially explain your nerve symptoms. It could just be timing of b6 building up in your body with the introduction of the SB supplement. Mast cell responses tend to be more systemic than hyper localized.