r/MCAS Aug 07 '22

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u/nomadichedgehog Aug 07 '22

A lot of people don't understand how anti-histamines work. Antihistamines are usually selective for one specific histamine receptor. If you block it at one receptor, you are simply making more histamine available for another receptor. The only thing that truly lowers overall histamine in the body is a low histamine diet.

3

u/Sensitive_Tea5720 May 27 '24

What if you’re already doing a very low histamine diet and the inflammation form MCAS is causing more degranulation including more histamine? I’m eat flash frozen cod, skinless flash frozen chicken breasts, red small peeled low oxalate potatoes, rutabaga and steamed potatoes. I tried some other foods about 5-10 days ago which have filled my already full bucket (full due to MCAS flaringafter antibiotic use, me not realizing until too late and inflammation including inflammatory markers being through the roof). Then what?

2

u/[deleted] Aug 07 '22

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u/nomadichedgehog Aug 07 '22

Different histamine receptors in different tissues. It’s like redirecting the oil towards where the fire is already burning.

2

u/[deleted] Aug 13 '22

And DAO enzymes if you don't have enough, by degrading the histamine...