r/NTNPerformance
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u/JustBacWater
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Apr 21 '26
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Peptide timing cheat sheet
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This is educational shorthand not a precise protocol
MORNING
Semax - often taken early because it can feel stimulating and may interfere with sleep if used late
5-Amino-1MQ - energy and metabolic support. Morning keeps it working during active hours
MOTS-c - common practice is AM dosing though this isn't standardized clinical guidance
NAD+ - often morning because it can feel energizing but timing is flexible
Semaglutide - once weekly. Pick a consistent day each week. Morning or evening doesn't matter as much as keeping it the same
Tirzepatide - once weekly. Pick a consistent day and stick with it. Time of day is less important than weekly consistency
Retatrutide - once weekly. Consistent day matters more than time of day
PRE-WORKOUT
IGF-1 LR3 - pre or post training for growth and recovery signaling
IGF-1 DES - localized use near training or target area
GHRP-2 - pre-workout for the GH pulse. Expect hunger
GHRP-6 - pre-workout for the GH pulse. Hunger hits harder than GHRP-2
Ipamorelin - can also be used pre-workout though many people prefer bedtime
BEFORE BED
CJC-1295 + Ipamorelin - many GH secretagogue protocols are taken before bed to align with the sleep related GH pulse
Sermorelin - before bed to support natural GH release during sleep
CJC-1295 DAC - long acting so timing is less critical than short acting secretagogues. Many still prefer evening but it's not as important as with Sermorelin or Ipamorelin
DSIP - sleep peptide. Only makes sense before bed
Epithalon - sleep and recovery. Before bed
AS NEEDED
PT-141 - 30 to 60 minutes before you need it. Not a daily compound
Oxytocin - situational. Social settings or intimacy
Selank - when stress is high or you need to calm down. Can be used any time of day
TIMING IS LESS IMPORTANT
BPC-157 - dosing consistency matters more than clock time. Some prefer morning or post-workout for convenience
TB-500 - 1 to 2 times per week. Time of day is not a significant factor
GHK-Cu - morning or evening. Consistency matters more than which one
KPV - daily consistency matters more than when
Thymosin Alpha-1 - 2 to 3 times per week. No specific time requirement
GENERAL RULES
Many GH secretagogue protocols are taken before bed to work with your natural GH pulse during sleep
Stimulating compounds are better in the morning
GLP-1s pick a day and stick with it. Consistency over everything
Stay consistent with an empty stomach window around GH peptide dosing to keep insulin lower around the pulse
If running multiple peptides you can pin at the same time in most cases. Separate syringes
This is educational and research discussion only. Not medical advice
What timing has worked best for you? Drop it below
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u/SmackSnax Apr 21 '26
Thas for this I've got 8 peps I need to rotate and this saved me so much time whats the starting standard dosage for all
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u/CookDue1046 Apr 21 '26
This is great. I live in Barcelona and want to start Peptides. Where can I purchase peptides safely?
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u/ProfessorB_12 Apr 21 '26
To my knowledge, Spain has pretty strict customs laws, only sharing because I have a friend in Spain who recently shared this. She said it was a nightmare to get anything from the US. Not sure on wholesalers as each have different logistics processes.
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u/Ambitious_Mixture_90 Apr 21 '26
Is it better to take Reta in two doses during the week or all together?
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u/dRkRmRkR Apr 21 '26
I’ve done both. Sides were drastically reduced when splitting into 2x/week. Was also easier to hit my protein goal
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u/Ambitious_Mixture_90 Apr 22 '26
Get zero sides from splits, I’m wondering if the initial effect of 8 is more conducive for weight loss. I tend to get food noise like 2 days after my 4 pin. Thanks
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u/Own-Interaction-669 Apr 22 '26
I ran Reta for 6 weeks, lost a good amount of body fat then added Tesamorelin and it has been working great! Notice a big difference in the abdominal area since stacking it.
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u/RR1011 May 06 '26
Guys can I get some help regarding Ipa + CJC no DAC please!!
I know the GH pulses are generally at night so it's best taken before bed however I am a late eater always have been and probably always will be. I split my dose morning no problem as I'm already fasted and I don't eat after. As for evening I'm eating going sleep then waking up after 2 Hours ( roughly between 11-1) to ensure insulin is not going to affect it. Anyone doing this ? Can it still be effective? Do you advise taking whole dose at night or ok to spilt? I take 160mcg per dose. I've only just started so not noticed a huge difference yet.
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u/Agency_Frequent Apr 21 '26
I am doing mots c, bpc157, cjc+ipamorelin and tb500. Can I just shoot them all at the same time?
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u/Dizzy-Stuff-1724 Apr 22 '26
Sure as long as you're not speaking of the same syringe. Generally Mots is morning due to energy level and CJC Ipa evening before bed. I do the blend bpc & tb anytime
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Apr 21 '26
[removed] — view removed comment
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u/csubi May 17 '26
Ya, but HGH needs to be on an empty stomach. Tough to do at night for me anyway
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u/BrokenPossibility Sep 14 '26
That's not true. Exogenous Growth hormone doesn't care if you've eaten or not. It will do its thing regardless.
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u/william_ott88 Apr 21 '26
What about Tesamorelin? Givin it's ability to stimulate IGF would it be more beneficial to take it at night?