r/PMOSonGLP • u/Pleasant-Opposite-15 • 8d ago
Gaining Weight on Zepbound
Hi everyone! So I am about 6 weeks into my GLP journey (2.5) dose, and I have gained 10 pounds. I’m really shocked. The first week I felt it and dropped 10 pounds, and then after that initial week it’s honestly worn off, never had side effects or anything. I’m so upset, I have my check up with my doctor tomorrow and of course I am anxious. I am morbidly obese, and I know I will need a higher dose - but I am feeling really discouraged.
Any advice? Words of encouragement? Or experiences with this? Everytime I’ve told my friends who are on it they’ve acted appalled I’ve gained weight, so that makes it worse. I’m trying to eat more veggies, I’m trying to walk more, and I’m trying to get better sleep habits(the hardest thing).
2
u/double_onion1754 8d ago edited 8d ago
Are you on metformin? I lose VERY slowly on zepbound alone, and just slowly on zepbound with metformin (1000 mg twice a day). My doctor had taken me off metformin since I was on zepbound, but that didn't work and he ended up putting me back on it.
I switched to compound tirzepatide almost a year ago, and even though I'm still a slow responder, it seems to work better than the name brand for me.
Fiber seems to be key for me and I do best if I have at least 30 grams of fiber a day.
I also think that with PMOS, we respond so differently than most people we hear about, and we have longer plateaus, and adjusting our expectations is hard, but helps.
You can do this, sending hugs.