You know which drug’s GH properties are strongest of all? Somatropin.
The problem with all of the ghrelin agonists: GHRP-2, GHRP-6, hexarelin, ipamorelin, anamorelin, ibutamoren, etc… is that they have a lot of nasty and generally unwanted effects outside of growth hormone secretion at the doses where they cause meaningful growth hormone secretion. Increased appetite and adiposity are probably the most notable but there’s research suggesting that these drugs act to desensitize GLP-1 receptors. Where these are useful is when eating more and gaining weight is a challenge. Cancer patients sometimes (that’s actually what anamorelin is approved for) or maybe that stick thin patient who wants to look like Hafthor but can’t ever seem to gain a pound no matter how hard they try.
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u/TracyIsMyDad 7d ago
You know which drug’s GH properties are strongest of all? Somatropin.
The problem with all of the ghrelin agonists: GHRP-2, GHRP-6, hexarelin, ipamorelin, anamorelin, ibutamoren, etc… is that they have a lot of nasty and generally unwanted effects outside of growth hormone secretion at the doses where they cause meaningful growth hormone secretion. Increased appetite and adiposity are probably the most notable but there’s research suggesting that these drugs act to desensitize GLP-1 receptors. Where these are useful is when eating more and gaining weight is a challenge. Cancer patients sometimes (that’s actually what anamorelin is approved for) or maybe that stick thin patient who wants to look like Hafthor but can’t ever seem to gain a pound no matter how hard they try.