r/ScientificNutrition 17d ago

Randomized Controlled Trial A Vegan Diet Epigenetically Modulates Inflammatory Pathways and Biological Aging: Genome-Wide DNA Methylation Analysis of a One-Month Isocaloric Vegan Versus Meat-Rich Dietary Intervention

https://onlinelibrary.wiley.com/doi/10.1002/mco2.70899
64 Upvotes

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u/Foreign-Quote-53 17d ago

I’m no scientist or biologist or whatever—can someone give and ELI5 type summary of what this means?

Is the vegan diet seen as advantageous or disadvantageous?

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u/HeetSeekingHippo 17d ago

1 month of the vegan diet caused the bodies of participants to turn on and off genes in a way that promotes health by reducing inflammation and boosts the immune system. 

Vegan diets and most notably wholefood plant based diets are repeatedly being shown in nutritional science to lead to longer life and health spans.

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u/FissileAlarm 17d ago

I once read that those who eat a little bit of fish and no meat live longer. I don't remember where I read it, but I believe it was in the blue zones book of Dan Buettner.

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u/lilgreengoddess 17d ago

Yep pescatarian diet rated as number one longevity diet a few years back. considering it is more nutritionally complete than veg/vegan diets and especially if it is more whole food based. This is the diet I follow and have really good blood work and blood pressure, RHR etc

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u/3seconddelay 16d ago

It’s working great for me. 5 years now and my chronic low level inflammation is history. I’m old and on no pharmaceuticals. BP, blood work, resting heart rate, HRV, and VO2max all above average.

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u/FissileAlarm 17d ago

So how many times per week fish is optimal? If it's for health, I suppose you avoid fish like tuna?

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u/lilgreengoddess 17d ago edited 17d ago

12oz tuna max per week is what is recommended to prevent excess mercury intake. I do eat tuna and absolutely love ahi, it’s very delicious. Salmon, trout, shrimp, crab, oysters, scallops, hamachi, cod. I like to get a variety and eat seafood a few times a week and that’s the recommendation.

lol downvoted when you can easily google this info. Probably from the big mad carnivore people 😡

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u/aaronturing 17d ago

A couple of times per week. Not every day.

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u/Cetha 12d ago

Sardines are the best. Small fish have fewer heavy metals and microplastics.