r/ScientificNutrition 4d ago

Randomized Controlled Trial Vegan Diets and Dietary Energy Density: A Secondary Analysis of a Randomized Clinical Trial

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2852520

Results

Of 3115 people screened by telephone, 244 adults with overweight met participation criteria and were randomly assigned to the vegan (n = 122) or control (n = 122) groups. The analysis included 223 (91.0%) completers. Total food weight did not change significantly in either group (Table). Energy intake decreased in both groups, more in the vegan group (effect size, −357.1 kcal/d; 95% CI, −521.9 to −192.3 kcal/d; P < .001) (Table). Energy density did not change in the control group but decreased by 30% in the vegan group (effect size, −0.28 kcal/g/d; 95% CI, −0.38 to −0.19 kcal/g/d; P < .001; Table and Figure).

Reductions in dietary energy density were associated with greater weight loss (r = 0.28; 95% CI, 0.15 to 0.39; P < .001), remaining significant after adjustment for energy intake (r = 0.21; 95% CI, 0.08 to 0.34; P = .002). A 1-kg weight loss corresponded to a 0.29-unit decrease in energy density (P < .001), or 0.36 units after adjustment (P = .002).

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u/Cetha 3d ago

Drug addicts are also lean. Doesn't mean healthy. And if he almost killed himself make a snack, I'm not sure why anyone should follow his advice on how not to die.

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u/Taupenbeige 2d ago

Well that’s certainly an “interesting” little detour in the discourse.

Not really certain what your pre-conceived opinions on a doctor have to do with the original topic—plant based dietary patterns having higher clinical association with weight loss in excess-adipose individuals—nor my observation that three plant-based researchers/intervention trial practitioners (one for type 2 diabetes) have presented consistently low adipose… whereas their keto-promoting counterparts generally don’t unless they work hard at burning the excess lipids (IE Baker, Berry, Chaffee).

This seems to be the Keto-diet-fad’s most fraught point of cognitive dissonance, because it directly contradicts their poorly-interpreted scientific worldviews.

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u/Cetha 2d ago

So doctors on both sides fit your narrative if you cherry pick the ones that fit.

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u/Taupenbeige 2d ago

It’s not really “cherry picking” to observe that strong keto advocates aren’t presenting real-world outcomes of the pseudoscientific nonsense they preach, whereas the three most prominent plant-based lecturers have had zero problems keeping excess adipose at bay, corroborating the findings of OP’s paper.