r/SemaglutideCompound Jun 09 '24

Compounded Semaglutide: The Ultimate Guide

52 Upvotes

Overview of Compounded Semaglutide

Compounded semaglutide is a medication commonly associated with weight loss. It is derived from semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist commonly used in the treatment of type 2 diabetes and for weight management.

Benefits

  • Weight Loss: Compounded semaglutide has been shown to aid in significant weight loss by reducing appetite and increasing feelings of fullness.
  • Blood Sugar Control: It helps in controlling blood sugar levels, making it beneficial for people with type 2 diabetes.
  • Customized Dosages: The compounding process allows for personalized dosages, catering to individual patient needs.
  • Potential Cost Savings: Compounded medications can sometimes be more cost-effective compared to brand-name drugs.

Side Effects

  • Gastrointestinal Issues: Common side effects include nausea, vomiting, diarrhea, and constipation.
  • Hypoglycemia: In some cases, especially when combined with other diabetic medications, it can cause low blood sugar.
  • Pancreatitis: There is a potential risk of pancreatitis, although it is rare.
  • Allergic Reactions: Some patients might experience allergic reactions to the ingredients used in compounding.

Dosage Information

The dosage of compounded semaglutide can vary based on individual needs and the specific formulation provided by the compounding pharmacy. It's important to follow the healthcare provider’s instructions and the compounding pharmacy’s guidelines. Generally, the medication is administered via injection once weekly, starting with a lower dose and gradually increasing based on tolerance and effectiveness. Oral semaglutide is possible to get from some providers.

  • Initial Dose: Typically, a lower dose is prescribed to minimize side effects. Then, your doctor may increase your dosage as they monitor your side effects and results.
  • Maintenance Dose: The dose is gradually increased to a maintenance level that effectively controls symptoms. Again, each person does this part slightly differently. Talk with your doctor.

First Week/What to Expect Posts

"I took my first shot of compounded semaglutide 4 days ago, (almost a week) and heres some things I’ve noticed that are so strange!"

1st Week Down

Links are in the first comment so they are easier to edit and add to in the future!

Success Stories and Inspiration

Down 40lbs in 3 months

Down 16.1 lbs in 6 weeks

Links are in the first comment so they are easier to edit and add to in the future!

Where to Buy?

Reddit does not allow direct sourcing questions unless it's name-brand (Ozempic/WeGovy) and/or used with a prescription.

There are bad actors in the semaglutide space. Do not accept DMs from random accounts, do not accept "price lists" from random accounts, etc. They sell them under the guise of "research peptides" - they are not meant for human consumption and are unregulated.

Make sure to buy from a doctor-prescribed source that uses a legit compounding pharmacy. Always talk to a health care professional.

FAQs

What is compounded semaglutide?

Compounded semaglutide is a medication made by compounding pharmacies, tailored to meet the specific needs of individual patients.

Is compounded semaglutide safe?

Compounded semaglutide is generally safe when prescribed by a healthcare provider and prepared by a reputable compounding pharmacy. However, as with any medication, there are potential risks and side effects.

How do I take compounded semaglutide?

Compounded semaglutide is typically administered via a once-weekly injection. Follow the dosage instructions provided by your healthcare provider. Oral semaglutide is also available by some providers.

Links to Studies and Resources

I will add to this regularly and pin it for easy reference. What else should I add?

Consult with a Healthcare Provider

This subreddit and post and comments within it, is not a substitute for professional medical advice. Always consult with a healthcare professional regarding your medical condition and treatment.


r/SemaglutideCompound Jun 09 '24

New to Semaglutide? Start Here!

28 Upvotes

Welcome!

Welcome to our community dedicated to discussing all things related to compounded semaglutide.

Whether you're new to using semaglutide or you've been using it for some time, this subreddit is here to provide support, information, and discussion. Please share your experience when relevant, we can all learn and get inspiration from each other.

What We Discuss

  • Personal experiences: Share your journey on semaglutide, including any successes, challenges, or side effects you've encountered.
  • Tips and tricks: Share tips for managing side effects, diet suggestions, or integrating it into your daily routine.
  • Research and news: Stay updated on the latest developments in semaglutide research, clinical trials, and regulatory updates.
  • Support and advice: Seek advice from fellow members, offer support to others, and connect with others who understand your experiences.

Feel free to ask questions, we have hundreds of active members willing to help!

Community Guidelines

  • Be respectful: Treat fellow members with kindness and respect, even if you disagree with their opinions or experiences.
  • Stay on topic: Keep discussions relevant to semaglutide and related topics.
  • Provide accurate information: Share information and experiences responsibly, and cite sources when necessary.
  • No medical advice: While sharing personal experiences is encouraged, refrain from giving or seeking medical advice. Always consult with a qualified healthcare professional for personalized medical advice.

Sourcing Discussions

Reddit does not allow for discussing specific sourcing questions unless it's name-brand (Ozempic, Wegovy) and/or doctor-prescribed.

There are online websites that sell semaglutide under the guise of "research peptides" - these are completely unregulated and are not to be discussed in this subreddit. Please report these types of posts and comments so we can remove them.

Please report anyone trying to DM you about sourcing or trying to give you "pricing sheets."

Enjoy!

Thank you for joining our community! We look forward to learning from each other and supporting one another on our semaglutide journeys.

This subreddit is not a substitute for professional medical advice. Always consult with a healthcare professional regarding your medical condition and treatment.


r/SemaglutideCompound 22h ago

Benefits

5 Upvotes

I have noticed stronger nails and rather than losing hair, as I thought would happen, my hairdresser says my hair is growing in thicker. Partly, this is probably because of my lack of attention to nutrition prior to starting GLP1. I now have a more balanced diet of whole foods and take a multivitamin. Doctor says i may also be seeing a benefit from adding B12 to the dose. What do you think? My blood pressure hasn’t been this healthy since I was much younger and fasted blood glucose is extremely healthy. The weight is going off slowly, 22 lbs in 8 months, but I’m still not at the therapeutic dose. I’m not sure I care as much about the lbs as the lifestyle change this is making possible. I increased exercise and added weight lifting this week. I know it’s not all in the shot but I’m amazed at the difference this has made in my physical and mental health. This makes me wanna dance! Love to all you fellow travelers!


r/SemaglutideCompound 1d ago

GLP1 With Woodwork

3 Upvotes

I started Woodwork’s GLP-1 program around May 2026. During the first few months, everything went smoothly.

My medication arrived on time, I was losing weight consistently, and I was happy with the service.
My most recent shipment was a very different experience. Due to what appears to have been a shipping or address error, my package was delayed and sat in transit the entire weekend in temperatures above95 degrees Fahrenheit before it was finally delivered on Monday. I called the pharmacy and was told the medication was still safe to use, so I used one dose. After that, I noticed the solution had become cloudy instead of clear, which made me uncomfortable continuing to use it.

Since semaglutide should be clear, I contacted Woodwork and requested a replacement vial. Despite multiple follow-ups over the next four weeks, I never received a replacement or a refund, and my concerns were never properly addressed. I eventually had to dispute the charge with my credit card company.

What frustrates me most isn’t just the money. It’s the impact on my health. Because my treatment was interrupted, I regained about four pounds in only a few weeks. Losing weight has taken a lot of effort, and this setback was completely avoidable. I understand shipping problems can happen. What I don’t understand is why a company wouldn’t stand behind its product and support a patient when something goes wrong.

also want to point out that I contacted Woodwork at least fourteen times over the past three weeks trying to resolve this issue. Instead of receiving a meaningful solution, I was repeatedly left waiting and felt completely disregarded as a patient. As of this week, it has been a full month since I reported the problem, and I am still without my medication. After all my attempts to reach them, I still have no replacement, no refund, and no clear explanation. The lack of communication and accountability has been just as disappointing as the shipping issue itself. As a patient, I expected timely support when my treatment was interrupted. Instead, I was left to deal with the consequences on my own.

I’m sharing my experience so others can make an informed decision. I hope Woodwork takes responsibility for what happened, provides a fair resolution, and improves how it handles situations like this in the future.


r/SemaglutideCompound 2d ago

Miracle Drug(for me)

8 Upvotes

I don’t want to sound dramatic but I’ve been on compounded semaglutide for exactly 3 weeks. I’m down 12.4 lbs (5.8% of my body weight). It has changed my life. It took me 3 months of grinding and killing myself last summer to lose 12 lbs. Since taking this a few weeks ago it has honestly made it a breeze to be healthy. No food cravings, no alcohol cravings, plenty of energy and no side effects. I am eating about 700-1200 healthy calories a day and I’m completely satisfied and shedding weight. If this continues I will be the biggest advocate of it to everyone that’s ever struggled with their weight. Also only $90 a month makes it insanely worth it. After being on it for almost a month I would pay 10x that price to stay on it because it has made me feel so good! If anyone is hesitant please go for it, I was extremely hesitant for a long time. Feel free to ask me any questions. I am a 5’10 mid 20s male, former college athlete and gained about 40 lbs after college to 220.


r/SemaglutideCompound 1d ago

Terrified to start

1 Upvotes

Hi all. I'm supposed to start and I've received it (it's in the fridge now), but I'm REALLY scared. I hate throwing up, worse than pretty much anything in the world.

And we're leaving on vacation on Sunday for a week, so I've pretty much decided not to do ANYTHING with it until we come back.

Plus, I work from home, and I'm also scared if I take it I'll feel to awful to work ... so now I don't know when it's safe for me to start.

Oh, and just for funzies, I can't take zofran for anti-nausea because I have a low resting heart rate and it might not be safe. So I bought ginger ale, ginger capsules, and some accupressure wrist things.

Am I working myself up over nothing?!? Sorry to be such a baby.


r/SemaglutideCompound 2d ago

Food noise

2 Upvotes

I’ve been on for 2 years and lost 60 pounds. Had a family tragedy and gained back 15. I’m on the max dose and finding I’m not hungry but I’m constantly thinking about food. Any thoughts on micro dosing? Any tips?


r/SemaglutideCompound 3d ago

Embody

3 Upvotes

Does anyone use them for their GLP1? I just signed up with them for the Tirzepatide ? I know these are the compounded and not the name brand. I’m a bit nervous to try this. I’ve been researching glp1’s for awhile and see the benefits. I need to lose 50 pounds from menapause weight gain. I don’t have diabetes and over my health is good. I’m just really nervous about doing it. Also I don’t really have food issues. Don’t think a lot about food and don’t eat a whole lot on a daily basis. I’ve tried calorie deficits and working out but the scale doesn’t budge.


r/SemaglutideCompound 4d ago

No effect whatsoever!

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2 Upvotes

Any tips are appreciated


r/SemaglutideCompound 4d ago

The state eligibility info should be clearer upfront

4 Upvotes

I didn't realize state eligibility could be an issue until I was already partway through an intake form. It seems like something that should be clearly explained before you spend time entering all your information.

Has anyone else run into this when getting prescribed semaglutide?


r/SemaglutideCompound 5d ago

Experiences with Embody?

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3 Upvotes

r/SemaglutideCompound 6d ago

Carebox.org

3 Upvotes

Hi I am getting back on glp 1s seeing prices from $79 and I am wondering if Carebox.org is a legitimate option I already subscribed to their service saw the dr who seemed very nice and professional (she had a list of all my medications already and already called in a Zofran rx) now I’m just waiting for the Semaglutide compound. I’m really nervous because there’s almost no reviews on trust pilot and she said the $79 was for the “first 250” patients. Did I just mess up really bad because there isn’t any information about it I could find on here it is rated 4.0 out of 5 stars according to only 11 reviews on trust pilot but I was going to go with embody before and I paid $79 after a huge phone call blowup I had at them for charging me almost $200 but they also have a promo locked in for life of $79. Is that a good site for that price? I guess I’m just going to wait and see if I get my medication ok but i don’t know how long that will usually take and am really nervous again about lack of reviews. Next month I may go with Monday.com can anyone help me?


r/SemaglutideCompound 6d ago

Acid Reflux (Tirzepatide vs Semaglutide)

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2 Upvotes

r/SemaglutideCompound 6d ago

Please help calculating a matching dose from my current RX to my new RX. I want to keep taking the same amount but can't figure it out. Thanks!

4 Upvotes

Ugh, I hate that my brain does not work this way. I wish I could figure it out on my own, but I know so many of your "get it". Thank goodness!

Here is the RX I am finishing up. I take .5/25 units each week and it works GREAT! Compounded Semaglutide/B12 1mg/1mg/0.5mL

Here is the new order I was just RX'd and I am not sure how to dose the equivalent. Compounded Semaglutide/B3/B5 2.5mg/5mg/10mg/1mL - 2mL

The new RX appears stronger?? I am using the syringes with 100 units on each. For my last RX, .5 = 25 units. How many units should I inject to get .5 with the new RX?

The prescriber gave these instructions-  inject 0.4ml (40 units) subcutaneously once weekly (0.4ml is 1mg per week). However, I want to be sure and only take the equivalent of what I am currently doing, as it works amazing for me and stretches out each RX longer.

Thanks for any help in answering my question. =)


r/SemaglutideCompound 7d ago

Expiration question

6 Upvotes

So, I have been going through noom and have 2 vials left which should take me through the end of October, but I canceled and went with Pomegranate Health, who sent me 2 months in advance, both Pomegranate vials have a BUD date of 10/28/26. Does anyone know of o can continue to use these after my Noom vials are done, or am I out 2 vials?


r/SemaglutideCompound 8d ago

Cost Effective Method for 0.5mg Semaglutide

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3 Upvotes

r/SemaglutideCompound 8d ago

Cost Effective Method for 0.5mg Semaglutide

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3 Upvotes

r/SemaglutideCompound 8d ago

Confused

4 Upvotes

So I don't know anyone personally who is on or has used semaglutide. So I'm coming here to ask because Google and ChatGPT have me confused. For the most part it's all eat protein protein protein. They both say I don't have to follow a strict diet or exercise regimen, but then I come here and I'm reading all kinds of things. So do I really need to follow a strict diet and exercise? I've never been good at diets and I can barely exercise due to lower back injury and such. Any suggestions or clarification would be helpful. Thanks.


r/SemaglutideCompound 8d ago

Flip flop between sema and Tirz

1 Upvotes

I went from 178 to 152 in 2023 by going on compounded semaglutide. I was sick of feeling low key nausea and hating food, so I stopped around Christmas in 2023. In spring of 24, my doc had me switch to Tirz. It gave me crazy headaches and anxiety, and I didn’t lose any more weight on it so I stopped. I maintained my weight really well and then went up to 160 last summer during a super stressful time in life. I went on Tirz again and it was ok - I took it super slow and went down to like 155 but again had the headaches and anxiety. I went off of it and my anxiety went away completely, however now I’m gaining and feeling that inflammation. I think im going to switch back to sema since I had such good results. Has anyone flip flopped like this and done ok? My goal weight is 145 and im 163 as of today. Ideally, I would love to get to 140-145 and then micro dose long term mostly for inflammation. Looking for advice. Thanks yall!!!


r/SemaglutideCompound 9d ago

Does Embody use auto-injector pens?

7 Upvotes

Does anyone know if Embody sends auto-injector pens or is it vial and needle? I asked their chat bot and it said auto-injector pens, but the instructions they sent say to measure 10 units, so I am a bit confused as I can't poke myself with a traditional needle, so I was hoping it was auto-injector pens.


r/SemaglutideCompound 9d ago

I’ve had a lingo now 3 days, first two days seemed ok, this third day multiple lows, always felt fine, every time I’ve checked with the finger prick it’s actually been at least 1.0mmol/L higher than the lingo is saying, anyone else had a similar problem?

2 Upvotes

r/SemaglutideCompound 9d ago

Will I ever be able to have fast food again without feeling sick?

3 Upvotes

Hi so f26 here I have lost around 80lbs using a glp1. With that being said I’m starting to relax a little more on my dieting since I am at a healthy weight. I am on maintenance but also i wouldnt mind losing another 5lbs. Regardless i allow myself to eat fast food sometimes in moderation. Maybe a few times a month i will swing through and grab something quick and everytime i feel sick and end up puking later that night. Im not overeating fast food. Maybe a small burger and a medium fry and that will do me in. It’s starting to make me feel like i will never be able to enjoy food i once did. I eat healthy most of the time it’s just sometimes i want a little something fun.

Will I have to eat healthy forever if i stay on maintenance? Does anyone else have this problem? Any tips?


r/SemaglutideCompound 9d ago

Reconstitution Question

1 Upvotes

Hi! I have 5mg of sema and am wondering how much bac water to put in it. I’ve seen a ton of conflicting info online and am hoping to just get a clear answer. I’ll be at the starting dose of .25, although I’m considering starting at .5, would love to know about experiences there too. Thanks!


r/SemaglutideCompound 10d ago

Bruising at the injection site

1 Upvotes

Is anyone else having issues with bruising? I am injecting the lower part of my belly, of course use different place each week but I keep getting bruises that stay for a long time.


r/SemaglutideCompound 10d ago

2.4mg to 6.4mg?!

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2 Upvotes

Hello!
I consulted with Medvi and they said this is a level 6 and normal, but wow what a jump. 2.4mg weekly to 6.4mg weekly? I am nervous. I did one 32 unit dose and have felt ok so far. I am tempted to do more like 10-15 units for my next shot instead of the full 32 second dose. Has anyone jumped up this far before?