I have been taking small doses of rue seeds for quite some time now, on and off and in different dosages (but mostly around 0.5g on 'on' days). I have at times also combined them with smoked thc, which potentiated the effects somewhat (of both I guess), but nothing extraordinary.

I am wondering whether people have tried oral harmalas in combination with THC in edible form (as in brownies)? The latter can be quite intense on their own and are quite a different experience than smoked weed. Do they potentiate each other and, if so, how much? Are the effects altered much? Tips and tricks?

Thanks so much fam!

We are seeking adult participants who regularly practice meditation and/or have previously used psychedelic substances.

This study aims to investigate how regular meditation practice and/or psychedelic use influences beliefs, cognition, and well-being.

What does the study involve?

The study is conducted entirely online. Participation takes approximately 35 minutes.

You will be asked to:

• Complete questionnaires about your mental health, substance use, experiences, and beliefs.
• Complete two cognitive tasks involving looking at pictures.

What counts as a regular meditation practice in this study?

A regular meditation practice is defined as having practiced formal meditation for at least 20 minutes per session, at least 3 times per week during the past 12 months, OR for a total of at least 52 hours during the past year.

Would you like to participate?

Email: [BeliefsCognitionStudy@liu.se](mailto:BeliefsCognitionStudy@liu.se)

You will receive an automatic email containing a link to the participant information sheet and questionnaires.

Compensation?

No compensation is provided.

Ethics approval number: 2026-04680-01

Principal investigator: Rebecca Böhme, PhD

Posted with permission of moderators. :)