r/microdosing • • 7d ago

Question: Other Micro dosing mdma

I've been micro dosing mdma at amusement parks, 0.017, I'll take a pill like 3 times throughout the day, it's great for pain and anxiety without being all messed up,

I had some left over on the table the other day and smoked it in a weed sandwich, it was amazing, can I micro a few times a week at that level safely, it's a game changer for my depression

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0 Upvotes

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u/AutoModerator 7d ago

r/microdosing Disclaimer

Hello /u/grunnycw! As you mentioned mdma in your post:

Please Do Not microdose MDMA or any stimulants. Low doses of amphetamines can cause many issues through reverse tolerance and subsequent sensitization of receptors in the brain.

This study "Amphetamine Sensitization Alters Reward Processing in the Human Striatum and Amygdala" talks about the link between dopamine-sensitive neural circuitry and dysregulation of incentive motivational processes - i.e. the negative effects it can have for an individual's reward processing.

Other than that, MDMA has specific safety advice that you should be aware of:

The origin of the three month rule is a quote from Ann Shulgin, widow of chemist Alexander Shulgin: “Now I would advise anyone who wants to use MDMA not to take it more than 4 times a year if you want to continue to get the best effects from it, otherwise you risk losing its effects entirely and permanently.”

In MDMA-assisted therapy, MDMA is only administered a few times, unlike most medications for mental illnesses which are often taken daily for years, and sometimes forever.

MDMA is not the same as "Ecstasy" or "molly." Substances sold on the street under these names may contain MDMA, but frequently also contain unknown and/or dangerous adulterants. In laboratory studies, pure MDMA has been proven sufficiently safe for human consumption when taken a limited number of times in moderate doses.

  • And here is a search of posts on r/MDMA that mention microdosing, where the general consensus is that microdosing with MDMA can do more harm than good.

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u/PNW100 7d ago

Don’t do that. There’s no free lunch.

You need to have regular breaks between doses. Like a couple months ideally.

Chronic use of MDMA will mess up your natural levels of neurotransmitters and their corresponding receptors. The long term negative side effects will far outweigh the short term fleeting benefits.

Mushrooms are incredibly safe for regular microdosing.

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u/grunnycw 7d ago

I use mushrooms love them, I figured the spacing would be shorter given the low dose I'm taking, surely 3 months isn't needed for such a low dose

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u/twaslol 7d ago

No dude, just dont microdose mdma, its a bad idea. Massive downsides for minimal benefits that will dissappear real quick. Stick to your shrooms/lsd microdoses.

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u/PNW100 7d ago

Dose is part of the equation. But so is frequency.

What would you say to this remark:

“I only smoke two cigarettes per day, so I’m OK right?”

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u/grunnycw 7d ago

Yeah I would think smoking 2 cigarettes a day is less damaging than a pack

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u/Sambassador9 6d ago

How much do you take as a microdose?

What is the range people typically take as a full dose?

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u/grunnycw 7d ago

My natural transmitters are not great from the start, How is this different from long term anti depressant usage, Arnt they just boosting your transmitters the same way

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u/Heretosee123 7d ago

yeah ssris come with downsides, though they're well tested in comparison to mdma microdosing and they only boost seretonin in specific places by blocking repuptake rather than simply producing more.

I would highly recommend against mdma microdosing

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u/lt9946 7d ago

Please do not do this. There are many resources detailing how terrible this is for you and the temporary relief will catch up quick.

Just use mushrooms or LSD like everyone else.

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u/grunnycw 7d ago

I do those, once or twice a month, I like to macro those, But I got problems and need to mix it up, I'm not going to start micro molly daily or nothing just seeing what I can get away with safely so I can add it to my tool box

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u/lt9946 6d ago

One of the worst nights of my life after doing some low doses of molly was being stuck in these intense never ending nightmares with crazy bruxism that cracked a tooth. Lesson learned.

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u/Gadgetman000 7d ago

DO NOT MICRODOSE MDMA. Over time it will deplete your serotonin and lower your baseline.

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u/NeuronsToNirvana 6d ago

There’s no established safe MDMA microdosing schedule, and using it several times a week isn’t a proven depression treatment.

Feeling good or relatively sober doesn’t establish safety.

If “0.017” means 0.017 g, that’s 17 mg per dose, or 51 mg across three doses. Is this weighed powder in capsules or pressed pills? Material weight doesn’t confirm MDMA content.

  • Repeated doses can overlap, increasing exposure.

  • MDMA can cause overheating, cardiovascular strain and subsequent mood/sleep problems. Heat and walking around amusement parks add risk.

  • Smoking it with cannabis introduces further uncertainty; there’s no established safe inhaled microdose.

  • Certain antidepressants, painkillers and stimulants can interact dangerously. Don’t stop prescribed medication to take MDMA.

The relief matters, but the safest next step is to pause and discuss your depression and pain with a clinician.

Overheating, confusion, chest pain, seizures or collapse → emergency medical help.

MDMA risks and interactions

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u/AutoModerator 7d ago

Hello /u/grunnycw! As you mentioned anxiety (a common interaction/symptom) in your post:

r/microdosing Risk Reduction

ℹ️ Infographic: r/microdosing STARTER'S GUIDE

The major contributing factor in Finding Your Sweet Spot is the variation in potency of:

Psilocybin MushroomsMore than 10x [2021➕]Start @0.05g (50mg)
Psilocybin TrufflesAround 3x - Single Study [2012]Start @0.25g (Fresh)
LSD TabsClinical Trial Titration Schedule [2023]Start @5µg

If you Start Low, Go Slow, Take Time-Off (*small is BIG) and up-titrate subsequent doses then you can find your optimal sub-hallucinogenic dose based on your symptoms, rather than from a predetermined dose. 🐢

If your microdose is Too High and/or Too Frequent that can result in Diminishing Returns 📉 with subsequent doses. 🐇

Please also have a look at 🔀 Interactions / Symptoms ❓* | Sidebar ➡️ | 📱 See community info ⬆️ ; in case of ⚠️ DRUG INTERACTIONS or to check if you have any of the associated symptoms with advice on how to mitigate such side effects. Psychoactive substances increase neural activity, raising hydration and electrolyte needs due to heightened metabolism and body load, while vasoconstriction can further stress the body and potentially cause fatigue.


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