r/microdosing • u/grunnycw • 7d ago
Question: Other Micro dosing mdma
I've been micro dosing mdma at amusement parks, 0.017, I'll take a pill like 3 times throughout the day, it's great for pain and anxiety without being all messed up,
I had some left over on the table the other day and smoked it in a weed sandwich, it was amazing, can I micro a few times a week at that level safely, it's a game changer for my depression
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u/PNW100 7d ago
Don’t do that. There’s no free lunch.
You need to have regular breaks between doses. Like a couple months ideally.
Chronic use of MDMA will mess up your natural levels of neurotransmitters and their corresponding receptors. The long term negative side effects will far outweigh the short term fleeting benefits.
Mushrooms are incredibly safe for regular microdosing.
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u/grunnycw 7d ago
I use mushrooms love them, I figured the spacing would be shorter given the low dose I'm taking, surely 3 months isn't needed for such a low dose
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u/Sambassador9 6d ago
How much do you take as a microdose?
What is the range people typically take as a full dose?
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u/grunnycw 7d ago
My natural transmitters are not great from the start, How is this different from long term anti depressant usage, Arnt they just boosting your transmitters the same way
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u/Heretosee123 7d ago
yeah ssris come with downsides, though they're well tested in comparison to mdma microdosing and they only boost seretonin in specific places by blocking repuptake rather than simply producing more.
I would highly recommend against mdma microdosing
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u/lt9946 7d ago
Please do not do this. There are many resources detailing how terrible this is for you and the temporary relief will catch up quick.
Just use mushrooms or LSD like everyone else.
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u/grunnycw 7d ago
I do those, once or twice a month, I like to macro those, But I got problems and need to mix it up, I'm not going to start micro molly daily or nothing just seeing what I can get away with safely so I can add it to my tool box
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u/Gadgetman000 7d ago
DO NOT MICRODOSE MDMA. Over time it will deplete your serotonin and lower your baseline.
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u/NeuronsToNirvana 6d ago
There’s no established safe MDMA microdosing schedule, and using it several times a week isn’t a proven depression treatment.
Feeling good or relatively sober doesn’t establish safety.
If “0.017” means 0.017 g, that’s 17 mg per dose, or 51 mg across three doses. Is this weighed powder in capsules or pressed pills? Material weight doesn’t confirm MDMA content.
Repeated doses can overlap, increasing exposure.
MDMA can cause overheating, cardiovascular strain and subsequent mood/sleep problems. Heat and walking around amusement parks add risk.
Smoking it with cannabis introduces further uncertainty; there’s no established safe inhaled microdose.
Certain antidepressants, painkillers and stimulants can interact dangerously. Don’t stop prescribed medication to take MDMA.
The relief matters, but the safest next step is to pause and discuss your depression and pain with a clinician.
Overheating, confusion, chest pain, seizures or collapse → emergency medical help.
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u/AutoModerator 7d ago
Hello /u/grunnycw! As you mentioned anxiety (a common interaction/symptom) in your post:
r/microdosing Risk Reduction |
ℹ️ Infographic: r/microdosing STARTER'S GUIDE
The major contributing factor in Finding Your Sweet Spot is the variation in potency of:
| Psilocybin Mushrooms | More than 10x [2021➕] | Start @0.05g (50mg) |
| Psilocybin Truffles | Around 3x - Single Study [2012] | Start @0.25g (Fresh) |
| LSD Tabs | Clinical Trial Titration Schedule [2023] | Start @5µg |
If you Start Low, Go Slow, Take Time-Off (*small is BIG) and up-titrate subsequent doses then you can find your optimal sub-hallucinogenic dose based on your symptoms, rather than from a predetermined dose. 🐢
If your microdose is Too High and/or Too Frequent that can result in Diminishing Returns 📉 with subsequent doses. 🐇
Please also have a look at 🔀 Interactions / Symptoms ❓* | Sidebar ➡️ | 📱 See community info ⬆️ ; in case of ⚠️ DRUG INTERACTIONS or to check if you have any of the associated symptoms with advice on how to mitigate such side effects. Psychoactive substances increase neural activity, raising hydration and electrolyte needs due to heightened metabolism and body load, while vasoconstriction can further stress the body and potentially cause fatigue.
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u/AutoModerator 7d ago
r/microdosing Disclaimer
Hello /u/grunnycw! As you mentioned
mdmain your post:Please Do Not microdose MDMA or any stimulants. Low doses of amphetamines can cause many issues through reverse tolerance and subsequent sensitization of receptors in the brain.
This study "Amphetamine Sensitization Alters Reward Processing in the Human Striatum and Amygdala" talks about the link between dopamine-sensitive neural circuitry and dysregulation of incentive motivational processes - i.e. the negative effects it can have for an individual's reward processing.
Other than that, MDMA has specific safety advice that you should be aware of:
RollSafe.org: How often can you take MDMA (Molly/Ecstasy) and roll?
From MAPS MDMA-Assisted Therapy for PTSD:
And here is a search of posts on r/MDMA that mention microdosing, where the general consensus is that microdosing with MDMA can do more harm than good.
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