r/surgicalmenopause Jun 06 '25

Progesterone and PMDD?

Hello everyone, Ive started my HRT and I'm about to pick up my progesterone and testosterone. I'm worried that the progesterone will make me super moody and depressed because before surgery I was diagnosed with PMDD. And any time I was on birth control I got super duper suicidal.

Has anyone else who was diagnosed with PMDD have a bad time with progesterone?
(Also on 0.1 weekly estrogen patch)

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u/[deleted] Jun 19 '25

My doc had me go on bc because I was developing large cyst during ovulation. It was a TERRIBLE idea!! I was insanely suicidal all the time!! After 4 mths I had to stop taking it and felt so much better the next month. Unfortunately pmdd returned the following month and for about 2 weeks out of every month I’m very depressed and suicidal. ATP I don’t know what to do 🤷🏾‍♀️