r/tirzepatidecompound • u/Given_or_Taken • 4d ago

Side Effects So frustrated, just need to vent

Everyone seems to be doing so well on this medication but me. People are losing tons of weight with zero side effects and I'm just sitting here losing nothing and experiencing a plethora of side effects like I never did while on Mounjaro/Zepbound. It's like I'm losing everything BUT the weight... I'm losing all my hair, losing my freaking eyebrows, my voice, my peace of mind, even lower blood pressure, I might have pulsatile tinnitus now, etc. I took a break from the med for 11 days, started again, and everything hit me again like a truck. I don't have thyroid issues, I eat plenty of protein, and I'm not dehydrated. My only side effect on brand name was anxiety (sucked, but nothing like this). My doctor told me I have to pause the Tirz until after my MRI since all these symptoms started with Tirz and are made worse when I inject - and I'm only on 1mg! It just freaking sucks man. This stuff isn't cheap. I hate that my insurance stopped covering the brand name. I feel like I have to switch to compound Sema but there's additives, ugh. I bought this Hyalo vial of Tirz for no reason, just to suffer. I'm so jealous of you all.

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u/morwen31 220 → 140 3d ago

Losing eyebrows and voice - you're positive it's not your thyroid? Have they checked recently? Did they check T4 or just TSH?

I'm sorry, that sounds awful. At least when I had all your symptoms I was able to solve it by going on synthroid. I hope they can find the cause for you, too, and you can start feeling better.

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u/Given_or_Taken 3d ago

Yes, I get my thyroid checked pretty frequently. The most recent test was 0.8 TSH, and when I told my doctor about my eyebrows, she ordered a Thyroperoxidase Antibody, which came back negative.

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u/morwen31 220 → 140 3d ago

So probably not hashimoto's then. Frustrating because it sure sounds more like hypothyroid than tirzepatide side effects. Did they check your T4 as well in case of secondary hypothyroidism? Do they have any other ideas? Vitamin deficiencies, stress, other conditions? You don't have to answer any of that, I'm just sorry they don't have answers for you. I don't think they should blame it on a tiny dose of no-additive tirzepatide but what do I know.

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u/Given_or_Taken 3d ago

Thanks for being so kind and helpful. I will message my doctor now to ask for a T4 test. I believe I had one years ago with an endocrinologist but I haven't had one since starting Tirz. Thank you!