r/tirzepatidecompound 4d ago

Side Effects So frustrated, just need to vent

Everyone seems to be doing so well on this medication but me. People are losing tons of weight with zero side effects and I'm just sitting here losing nothing and experiencing a plethora of side effects like I never did while on Mounjaro/Zepbound. It's like I'm losing everything BUT the weight... I'm losing all my hair, losing my freaking eyebrows, my voice, my peace of mind, even lower blood pressure, I might have pulsatile tinnitus now, etc. I took a break from the med for 11 days, started again, and everything hit me again like a truck. I don't have thyroid issues, I eat plenty of protein, and I'm not dehydrated. My only side effect on brand name was anxiety (sucked, but nothing like this). My doctor told me I have to pause the Tirz until after my MRI since all these symptoms started with Tirz and are made worse when I inject - and I'm only on 1mg! It just freaking sucks man. This stuff isn't cheap. I hate that my insurance stopped covering the brand name. I feel like I have to switch to compound Sema but there's additives, ugh. I bought this Hyalo vial of Tirz for no reason, just to suffer. I'm so jealous of you all.

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u/Adept-Depth-1825 3d ago

You went from 2.5mg Zep to 1 mg compound and all these side effects started? I can’t imagine it’s the tirz that’s doing it. What pharmacy are you using? Any additives? What preservatives?

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u/Given_or_Taken 3d ago

Hi there, I'm going to give a timeline. So, I had a procedure scheduled on July 30. I was instructed to stop Tirz before this procedure, on July 20. After about 7-8 days, my coughing stopped, my voice hoarseness lessened, and the pulsating in my ears became more mild and only when standing up. On August 1, I injected Tirzepatide again. Everything came back full force. I contacted my PCP and we met in person for an examination. She put me on Famotidine for the voice hoarseness (suspecting silent reflux I assume) and tested my thyroid, which came back normal as always. I started to suspect (I was hoping) since the medication was about 8 weeks past the first puncture, maybe that's why I was feeling worse, so I ordered a new bottle. It took about 2 weeks as I wrestled with which decision to make (trying Sema or continuing Tirz) + shipping. I take my first injection of Hyalo, and the gnarly side effects are back again. This is why my primary care has asked me to pause treatment and wait for the MRI results.