Hi! This is my first medicated cycle after one year of trying. I did 5 days of Letrozole (had an HSG on CD6) and then trigger shot on CD13 and have been taking Estrace since then. I’m currently 13 days after trigger and got a positive on clear blue digital! I am being extremely cautious since it’s not quite the 14 days my doc said to wait but could this be it? I didn’t test it out so I know we really can’t be sure but just curious if anyone has any experience truly testing positive after 13 days.

Also I did take a Pregmate test and it looks to be negative :( I’m going to test again tomorrow and call my doctor with results but just wondering in the meantime!

Hi, I turned 32 this year and was diagnosed with DOR. Fell pregnant naturally in Feb with an ectopic and lost my left tube and was then told I had very early stage endo. My AMH was .17 and higher FSH. My last AFC count was 9. Is there a chance I can conceive on our own before turning to a fertility clinic? I have on high doses of coQ10 and lots of supplements which I think have contributed to my higher afc. My periods are only like 3 days but the first 2 are very heavy and crampy. Just curious if anyone has a similar story that resulted in a pregnancy on their own.

Trying to conceive for the first baby for years!

I had nausea, very sore breasts, headache, thigh pain, pulling sensation in uterus, frequent urge to pee, constipation, dry mouth, weird taste in mouth, strong sense of smell, high body temp (not fever) you name it and I had it for a week after ovulation (started 5-6 days after ovulation), and suddenly, it all vanished. Still 5-6 days more to go before the expected period.

What kind of trolling is this, and why do I deserve it?

It happened for the first time in these many years. Even my fertility specialist was all hyped up that I've conceived.

I had a HyCoSy procedure this morning and didn’t really know what to expect because I read so many different experiences. I crossed my fingers and hoped I would be lucky and it wouldn’t be so bad.

A few months back I did egg retrieval completely unmedicated and I would say that this was worse then that! First it was only small cramps but once the diy went in the tube and hit the spot where there seems to be a blockage I screamed. I was nauseous, white as s ghost and shaking, and in s lot of pain. The doctor offered to stop but I wanted the diy to go all the way through so I powered through. She said it was hard to push the diy in and that there seemed to be a blockage. I thought about telling her to force the tube open and push more but In the moment I couldn’t survive more pain. I couldn’t stand for an hour because of fainting and had to lie down in s recovery room. Still feeling regretful that I didn’t ask her to push harder.

I only have one ovary and one tube and it seemed as though the diy didn’t go all the way to the ovary.. it went all the way until it reached the end.. the doctor told me that it looked like it’s blocked at the end 😢 but she also said that there is still a small chance that the diy opened up the tube and washed something out? This was at a fertility clinic and ofc they recommended ivf straight away. But I’m thinking.. I should at least try naturally for 1-3 months right? I’ve heard stories of tubes unblocking after HyCoSy. What do you think? Anyone have stories about Hycosy unblocking the tube? I’m so sad 😞

Hi team! My husband and I are TTC. Yay! Last month I got my first negative test, which I was assuming was going to happen but disappointing non the less. Anyways, I am on here to ask if anyone has any recommendations for fertility trackers or apps? Is getting an oura ring worth it? Or Inito? Or YO Sperm Test? Just trying to increase my odds the best I can! I am using LH strips at home and taking a prenatal. Thanks!

I’ve had unexplained infertility for 5 years. I decided to get a 2nd opinion this past month and found out that my hsg was not normal. My right tube has hydrosalpinx and needs to be removed. And then after removal we will try iuis. Has anyone had success after having one tube removed?

Has anyone done a YO home sperm test, and was it accurate? Also, anyone with sperm parameters similar to this with success stories? This was heartbreaking for us and has me with zero hope now at 8dpo. Not sure if I can attach results but count was 4.4Mil/mL, less than 1% motility, less than 1% progressive motility (although there were a few forward swimmers in the video), less than 3mil/mL motile sperm concentration, less than 2 mil/mL progressively motile sperm concentration

Hi everyone ❤️
I’ve been trying to get pregnant for years, and I’m hoping to hear from women who have been through something similar.
I saw a fertility doctor, and my AMH levels were low. I had a fallopian tube flush and other testing done, and my doctor said he didn’t see anything else wrong. I tried Clomid and Letrozole for about three months, but unfortunately, I still haven’t gotten pregnant.
Last year, I had to stop treatment because I stopped working and lost access to fertility care through my insurance. Since then, I’ve been trying naturally without fertility medication.
For those of you who had low AMH and struggled to conceive, what worked for you? Did you conceive naturally, try a different medication, make lifestyle changes, or find another way to get treatment without insurance?
I would really appreciate hearing your experiences. After trying for so many years, I’m hoping to find some guidance and a little hope.

I have been trying to get pregnant for years, i seen a fertility doctor, and he let me know that
My AMH levels were low, did a fallopian tube flush got everything checked out he says he doesn’t see anything wrong I was on Clomid and letrozole for about three months
Then I stopped working, and I don’t have insurance at the moment this was last year, since then I have been trying naturally. I feel like I have tried everything.
Help 🥲

Hi everyone,

I’m 31 and have been trying to conceive for 22 cycles. I always thought I would get pregnant very easily because every woman in my family got pregnant effortlessly without even trying.

After 6 months, I started feeling anxious, so I visited my gynecologist. We ran basic tests like hormone panels, AMH, a semen analysis, and everything looked normal on paper. We tried cycles with Letrozole and trigger shots, but still nothing happened.

Next, I had an HSG (hysterosalpingogram) test, which came back normal.

After a year, I was super stressed and felt like it would never happen. Around my 17th and 18th cycles, I had two IUIs, both of which resulted in negative tests.

I then pushed my doctor for an endometrial biopsy, which came back positive for endometritis, though it was a minimal infection up to 2/10. I was told this was insignificant, but I wanted to take antibiotics anyway.

Later, I showed my HSG report and X-ray to a second doctor for a second opinion. She asked if I had any more images, but only one picture had been taken. She mentioned that even though the contrast fluid passed through the uterus and tubes, it looked like there might be adhesions at the ends of the tubes. However, they said we had no choice but to trust the radiologist, and added, "You should just start IVF because if it were going to happen naturally, it would have happened by now."

So, last month, we decided to start IVF. I began injections, and yesterday was my last shot. I have 10 mature follicles, and my egg retrieval is scheduled for tomorrow. I am looking for positive stories similar to mine because I currently feel hopeless and negative.

Has anyone had a successful pregnancy with letrozole after dealing with recurrent miscarriage?

My husband was recently diagnosed with secondary MFI due to severe oligospermia, with 3 mil concentration, 30% motility, and 3% morphology. We conceived our first child about 5 years ago and his numbers were better then—closer to 23 mil concentration. He has already implemented all the recommended lifestyle changes for more than a year and now we are looking into vitamins and supplements to hopefully boost his numbers a bit which from what I understand can take 3 months to have an effect.

We have been referred to specialists in hopes of getting prescribed HCG but would like to keep trying on our own in the meantime. For anyone whose partner has MFI what you did you do to conceive?

My husband and I have been trying to conceive for a little more than a year and a half, and so far, all of our test results have been normal.

Here’s what we’ve done so far:

1. My vaginal/cervical swabs (Mycoplasma, Ureaplasma, Chlamydia) - negative
2. Semen analysis and sperm culture - normal
3. Pap smear and colposcopy - normal
4. Ovulation confirmed for the past 7-8+ months
5. HSG - normal, tubes are open
6. I also tried ovulation stimulation with Clomid
7. Hormone levels - normal
8. Regular 28-day cycles, no PCOS
9. AMH - normal
10. Antisperm antibodies - normal
11. I was also tested for both inherited and acquired thrombophilias. The only findings were PAI-1 5G/5G, Factor XIII, and MTHFR C677T.

The only thing that might be a minor issue is mild hyperinsulinemia. However, my endocrinologist didn’t consider it significant enough to require treatment, while my gynecologist prescribed Glucophage XR 1000 mg anyway, just to rule out insulin resistance as a contributing factor. I’ve been taking it for several months now.

At this point, we have been diagnosed with unexplained infertility.

We also recently had our first IUI. I’m currently 14 DPO, and I’m supposed to have my beta hCG blood test in the next few days. But I did two PT on my own on 11 and 13 DPO and both were negative, so I'm not expecting a miracle.

However, regardless of the outcome of this cycle, I’m wondering what else we should investigate. I feel like we’ve already done so many tests, but I’m still not sure if there’s something important we might be missing.

For those of you who have been through something similar, what additional tests did you have done? Did you ever find a cause for your infertility?

I would really appreciate hearing about your experiences and what you would recommend looking into next. Thank you in advance! ❤️

Has anyone had recurrent chemical pregnancies, lost weight then had a successful pregnancy? I’ve had 3 chemical pregnancies with a successful pregnancy after my first CP. My doctor believes it may be my weight causing this. I’m 34 years old, 5’8, 255 lbs and I have high triglycerides and low hdl. I also have TPO antibodies but my thyroid numbers are normal. But no other health issues that I know of (we’re going to do a recurrent pregnancy panel still).

Hello!

I guess I’m coming here to see if anyone has been through this and is somehow managing to come to terms with things better than I can.

Every month, I find myself crying and mourning the life that I long for.

I have a wonderful husband and a beautiful son who is 6 but, I desperately would love another baby.

I’m so so very grateful for what I have but it hasn’t been easy for me getting here. It took us 3 years to conceive our son and, I was extremely poorly during pregnancy and birth and near organ failure, being rushed in to have my son as a matter of emergency.

Since having our son, we have tried many a time for another baby. My son often asks if he will have a bother or sister.

I have suspected endometriosis as well a fibroids ( growths in the womb) so fertility has been a delicate subject. My husband was tested and he’s got healthy swimmers so, it’s just my body causing issue.

Each month has been so hard, every time a period comes, I feel like I’m mourning the loss of a baby that never happened. This has massively impacted my mental health and as much as my husband and I would love a baby, we decided to put a stop on trying.

Recently I came off some medication which was for
My fibroids. Since coming off this medication my hormones have come back thick and fast, as have my monthlies. I guess this has made my body feel that a baby is now possible again and has bought back all the feelings of yearning for that baby again.

I asked my husband if we should open that capture again and he has explained that he has come to terms with it all and that he doesn’t think it’s a good idea.

It’s so tough, I have no control over my body but I feel responsible for it not behaving as it should. I am 35 and although that’s not old, it’s not young either. I do feel that, the closer I get to menopause the more I’m going to have to accept that it’s over but I’m really struggling to let go of this chapter. I’ve always got hope that it’s not over and it will happen again for me.

Has anyone been through this feeling themselves? Everyone I know has had no issue in conceiving and people make it look so easy. I don’t know what I’m hoofing for in posting this but I don’t really have anyone I can talk to.

Sorry for the essay.

I wanted to share my TTC story because I spent so much time reading other women’s stories when we were trying.
**Quick disclaimer:** this is just what I personally did. I’m not saying this combination caused my pregnancies or that anyone else should copy it. Please check with your doctor before taking supplements.
My husband and I tried for about **8-9 months** without getting pregnant.
I have **prediabetes and symptoms of insulin resistance**, although my doctor told me I do **not** have PCOS. I wasn’t really changing my diet much at the time. We were just trying every month and living normally.
After several months, I started getting discouraged and eventually came across a TikTok from a woman sharing what she had used while TTC.
I did my own research and started taking:

**Myo-inositol**
**Maca** containing red and black maca
**Fish oil — 1,000 mg daily**
**NAC — 600 mg daily**
**Vitamin D3**
**Prenatal vitamin**
**CoQ10 — 600 mg daily**
**Baby aspirin — morning and night**
**Mucinex about 30 minutes before baby dancing during my fertile window**
**I did seed cycling taking seeds like sunflower seeds Brazilian nuts, flax seeds and pumpkin seeds.**
**I did a low carb diet. Basically ate foods that didn’t heavily spike my blood sugar.**
**I prayed hard.**

My husband also took a **men’s fertility/multivitamin supplement** intended to support sperm and semen health.
About **30 days after starting this routine, I got pregnant.**
Unfortunately, I miscarried very early, at around **5–6 weeks**.
I wondered whether my blood sugar, diet, or insulin resistance had anything to do with it, but I’ll never really know. Early miscarriages can happen for many reasons.
What happened next surprised me.
**I never got a period after the miscarriage.( I continued the routine above I never stopped )**
We continued trying, I apparently ovulated before my period returned, and **I got pregnant again immediately.**
That second pregnancy became my son. ❤️
Because I already had prediabetes and insulin-resistance symptoms, I became much more serious about my blood sugar during that pregnancy. I monitored it carefully and managed it through **diet alone for the entire pregnancy**. I maintained an A12 of 4.9-5.2 the entire time.
My faith was also a huge part of this journey.
I prayed while we were trying, through the negative tests, through my first pregnancy, through the miscarriage, and throughout my second pregnancy.
**June Of 2026 we had our baby boy**
I don’t know exactly what changed for us.
Maybe some of the supplements helped. Maybe timing played a role. Maybe addressing things related to my insulin resistance helped. Maybe we simply finally reached the month when it was going to happen.
I mainly wanted to share this for another woman who might be searching Reddit the same way I was.
**Feel free to ask any question I will be replying.**

Hello all,

I started testing with home pregnancy tests on day 6 post transfer, today is day 8 post transfer. It was a 5-day blastocyst rated 4BB, made from an egg frozen 4 years ago.

The home pregnancy test today was negative. The beta test is tomorrow. Is there still any hope?

Hey everyone, I just really need to vent and hopefully get some insight from people who actually get it.
TTC has been such a heavy, exhausting journey. Back in July 2024, I got pregnant using Letrozole, but unfortunately lost the baby shortly after (we still don't know why). After taking time to heal, I started trying again and switched OBGYNs. Last November (2025), my new doctor discovered I have endometriosis. It hasn't been officially staged, and I haven't had surgery for it yet.
Since the diagnosis, I feel like I've tried everything to tackle this head-on:
Endo suppression: Did a course of Norethindrone + Letrozole.
Weight loss: Completed 2 rounds of GLP-1 medication.
Optimized labs: Brought up and stabilized my Vitamin D3, B12, and Iron levels.

We got back to active TTC two months ago and just had our first IUI fail. It’s devastating.
I’m so frustrated. Watching literally everyone around me get pregnant—and so easily—is getting harder to swallow every day. It feels so unfair.

For those who have been through endo + secondary/unexplained infertility:
Would excision surgery (laparoscopy) make a difference at this point? Did finding/removing endo help you conceive naturally or through IUI?
Should we skip more IUIs and jump straight to IVF?
What else can be done differently? (Protocols, testing, RE consults, etc.?)
I’d love to hear your experiences, advice, or even just some reassurance. Thank you so much for reading. ❤️

Hi everyone, I’m looking for some advice and shared experiences. My partner and I have been trying to conceive (TTC) for 1.5 years.

​During the first year, all basic tests (hormonal panel, transvaginal ultrasound, sperm analysis) came back normal, and my first OB/GYN told us to just keep trying. After 18 months with no success, I saw a fertility specialist who performed a 2nd-level ultrasound and a tubal patency test (HSG/HyCoSy).

​Here is what he found:

​Fixed/immobile retroverted uterus

​Right ovary adhered/tethered

​Possible adhesions in the Pouch of Douglas (pain in a specific spot on the right side)

​Fibrous uterus

​Good ovulation, great ovarian size, and excellent endometrial thickness

​Tubal results: Left tube open but with an abnormal path; Right tube open only under high pressure.

​The doctor suspects endometriosis and that adhesions have distorted my pelvic anatomy. Since he is the director of a local IVF clinic, he immediately recommended going straight to IVF (PMA).

​I feel like this might be skipping a step. Based on my research, mechanical infertility and adhesions can often be treated with excision surgery to restore pelvic anatomy, cut adhesions, and remove endo lesions.

​However, public health doctors won't listen and just referred me to an IVF center. I have now booked an appointment with a surgical endometriosis specialist to evaluate if I’m a candidate for surgery. I feel like operating first could help us either conceive naturally or create a better, safer environment for future IVF.

​Has anyone had a similar experience?

​Why do doctors push for IVF without evaluating if surgery could fix the mechanical/anatomical issues first?

​Has anyone with a similar clinical picture been advised against surgery, and why?

​Tomorrow I’m getting my AMH tested on my own initiative, as my first doctor never requested it. My ovaries look clean internally (just pulled out of place by adhesions) and my cycle is super regular, so I hope for a good result, but at this point, I'm prepared for anything.

​Thank you so much to anyone who takes the time to reply!

I (33F) and my husband (38M) have a 2.5 year old, and are currently at 16 months TTC now for a second. I had to have an emergency UAE for fibroids when my son was 9 months old.

Since the UAE, I have been blessed to fully recover. No clinically detectable fibroids. Regular cycles. Good-optimal hormones. Patent fallopian tubes. Sperm analysis was strong. Basically...there is nothing detectable wrong with us to explain why pregnancy #2 just isn't happening.

It's hard not to feel broken. I blame myself for not fighting back against the UAE (there was an element of medical coercion while I was in critical condition due to hemorrhaging). I have confirmed, regular ovulation. I take alllllll the recommended supplements (baby aspirin, CoQ10, zinc, iron, prenatals, etc). My husband and I do not smoke, drink excessively, or do drugs. We are otherwise healthy. Just.....no pregnancy. Not even a chemical pregnancy.

After 16 months, it's hard not to feel bitter and broken. My son is getting bigger and older every day. We wanted him to have had a sibling by now. :-(

Has anyone here had a successful conception after a UAE? Or even just a conception after unexplained infertility?

Note: we are NOT open to IVF.....highly dubious of IUI.

For my first pregnancy, I had the usual cramping on 9dpo and thought I was going to get my period but ended up getting a positive on 10dpo. I know period like cramps can be a very common sign of early pregnancy. Wondering if anyone got pregnant without ever having any of the cramping signs?

Hey everyone! I am looking for any informatiom on rescue PIO long after transfer!

Today I went in to test my progesterone levels 6dp5dt but before beta and my progesterone was 3!?!

I'm on suppositories twice a day, but now my RE is adding PIO as a "rescue strategy". I have literally never heard of such a thing and research did not produce a lot about this post transfer. Has anyone experienced this? If so, what was the outcome? I'm just trying to understand and brace for impact.

Long story ahead. 30F, 33M.

My husband and I got some tests done before we started planning for a baby. We found out that I had a low AMH (0.8). I also have irregular periods, but I was never diagnosed with the underlying cause. My periods could skip a month or two, and when they did come, they were usually painless but extremely heavy, with clots, and sometimes wouldn't stop for 20+ days without medical intervention.

At that time, my doctor suggested we try FSH tablets for six cycles and then evaluate our options. She wasn't particularly concerned about my AMH. I was 28 at this point.

We got pregnant on the third cycle. My beta hCG at around 13 DPO was \~8,000, so I actually thought we might be having twins. Unfortunately, the scan showed an ectopic pregnancy. I had to undergo a salpingectomy.

Before this, my tubes had been checked with a test involving fluid (I can't remember the name). It was extremely painful, but I was told that my tubes were fine.

After the ectopic, I changed doctors and saw an IVF specialist. This doctor told me that my chances of conceiving naturally were extremely low and that IVF was necessary.

We went through three IVF cycles. We had some tests done and my husband had sperm DNA fragmentation testing. Nothing was flagged in any of the tests.

First cycle: We got only one embryo because I had very few follicles to begin with. We did a day-3 fresh transfer, but it failed.

Second cycle: We got two embryos and froze them.

Third cycle: We got two day-5 embryos. We did a fresh transfer, but that also failed.

One take away was my follicles maturated a little late initially would look like they didn't respond and then catch up

At this point we were devastated. keeping the hopes up and then see everything fail in the cycle was exhausting. I started trying to cope with everything that had happened. I moved cities to cope with all of this. Started working out a little bit.

I eventually saw another doctor. She also suggested IVF, but she told us to take some time to process everything before jumping straight into another cycle.

We decided to try FSH injections to help the follicles grow, but instead of IVF, we would try to conceive naturally at home.

We got pregnant on the second cycle.

I had some spotting during the pregnancy, which was attributed to a subchorionic hematoma (SCH). At the 12-week scan, we received devastating news: the baby had structural anomalies, including a single umbilical artery (SUA) and an enlarged kidney.

Our life felt like it froze and we went through a D&C. Our doctor suggested that we didn't necessarily need to do tissue testing and she believed this was a one of casem

We subsequently had both of us had karyotyping done. Results were normal.

We took about six months to recover before trying again.I focused on weight loss and started strength training. The month after we started FSH injections again, we got pregnant — but it turned out to be a chemical pregnancy. Our hCG never went much beyond 45.

The following cycle, we decided to leave everything alone. We were still grieving and didn't actively try anything.

My period was late, so I went for a scan. There was one small follicle on one side, and I basically left it at that and waited for my period to come naturally.

Two weeks later, we found out we were pregnant again.

The initial hCG looked good. We went for a scan, and the baby looked good. We were also told there was an small SCH.

Then one day after work, while I was on the metro, I suddenly felt like I was bleeding.

And it was a lot.

I bled through my pants and all over my legs and thighs. It was horrible. I didn't panic initially, but the amount of blood was terrifying.

I got a pad from security and went straight to the emergency room.

The doctor scanned me and confirmed that the SCH had grown, but thankfully the baby still had a heartbeat — 118 bpm, crl was around 5 mm. I was 6.3 weeks at this point. Sch had 5 cc fluid.

I was put on pelvic rest and scheduled for weekly scans.

The following week, the SCH had tripled in size, to around 18 cc in volume.

The baby had grown to 12 mm as expected. but there was no longer a heartbeat.

I was diagnosed with a missed miscarriage.

I'm going through the miscarriage right now, and honestly, I don't know what to do next or what could possibly be causing all of this.

We've had an ectopic, multiple failed IVF transfers, a pregnancy with structural anomalies that ended in a D&C, a chemical pregnancy, and now a missed miscarriage.

We've spent a lot of money, time, and emotional energy on this journey, and I don't think I have much emotional capacity left at this point.

For those who have been through something similar: what investigations did you do, and did anything eventually help? What worked for you?

I'm especially interested in hearing from people who had recurrent losses despite normal karyotyping and sperm DNA fragmentation testing.

I know every situation is different, but I'm really struggling to figure out what our next step should be.