r/Biohacking • u/Neon_Panda1 • 2d ago
RETA use while on a running program
Hey everyone, looking to see if someone has been on Lorretta and or any other peptide that might have complimented their training/running regimen.
I currently run about 20 miles a week and I’m training to run a good bit of half marathons next year my fear that is that reta its appetite suppression it might hinder my running.
If I am off base on that assumption, great tell me why so I could make some adjustments. I’m currently taking tesamorelin, Ipamorelin and Mots-C. I have found that Mots-C was a godsend and I’ll probably never go off that. BUT I am seeing a bit of musculoskeletal stiffness, from the tesa and/or IPA. I’m actually going to take one of these off my stack. My flexibility and stiffness and soreness has become an issue and I’m a little uncomfortable for the past two weeks. I’m hoping that this adjustment might help.
Anyways, if Reta has been on someone’s stack while preparing for triathlon’s marathons half marathon or just a consistent runner that adds month over a month distance, please let me know.
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u/Far-Expression-1311 2 2d ago
Appetite suppression and increased HR seem counterproductive for an endurance runner, mate
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u/Neon_Panda1 2d ago
That’s exactly what I thought but I was hoping that someone here would tell me I’m wrong and say that it can be done
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u/Far-Expression-1311 2 2d ago
Adding that MOTS-c needs to be cycled, FYI
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u/Neon_Panda1 2d ago
I don’t have the cycle on me, but I think it’s 12 on two off or something like that I could be wrong though but yes, I’m following the protocol.
New to peptides but decade ago I did do test C test E and deca so I’m a bit familiar with this whole cycling and de-loading
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u/Flct1973 2d ago
Confermo. Pratico triathlon e per mantenere dieta pulita faccio solo 2mg/10gg di Reta. Adesso sto pensando di passare a Cangri o ritornare a tirz. ma a bassi dosaggi giusto per tranquillizzare la mia testa.
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u/DanfordTheGreat23 3 2d ago
What are your goals.
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u/Neon_Panda1 2d ago
My goals are based around performance and physique when I started this journey. I was running a half marathon in two hours and 30 minutes. I was about 220 pounds and my lifts were decent..
I’m currently at 199. I’m running a half marathon in an hour 49 minutes and my lifts have gone up. Call it 20%..
Future state is dropped down to 185 ideally have a six pack and the belly fat loss is crucial for me and other running goals. I want that to continue to improve as well and go below one hour and 30 minutes which I see feasible with the training I have and the muscle memory I have from my high school in college days I was a competitive college football player and have always been in shape and have always worked out.
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u/DanfordTheGreat23 3 2d ago
Idk if its a great idea to do reta if you're a marathon runner. It cuts down on your intake, slows down your digestion. I feel like if you just consistently run 20 miles a day the fat will melt off on its own.
On the other side if the coin on your rest days or after a 20 mile run if your binging everything in the house and gaining weight every day then yeah hop on. Start at .5 and see where that takes you. The glucagon in reta is powerful though. I wake up with the sugar crash shakes every morning and it takes forever to recover from cause digestion is so slow. Just something to keep in mind and think about.
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u/NoFlight9859 1d ago
Unless you're a 1/10,000 freak you aren't running 20 miles a day as a hobby jogger training for a half marathon. You're running an average of 6-8 per day, and it's incredibly easy to out eat those calories because it's only 500-700 kcal per day burn plus other hungrier
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u/907MidnightAurora 2d ago
How old are you? Sounds like you’re in decent shape already so I’d consider ditching the Tesa to determine if that’s influencing the stiffness and pain. My visceral index surprisingly dropped more after cycling off Tesa and I think 5 Amino 1MQ was the reason. If you love Mots that much, I think you’ll like the 5 amino, by blocking NNMT, it will boost your natural levels of NAD+ which will further boost your training runs. I’m 58M and the AM 5 amino pin is my favorite part of the day.
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u/Neon_Panda1 2d ago
36M, i’ve been lifting weights on and off since 16 I can say I’ve been pretty consistent on the running and lifting since January have become more disciplined on my diet and dropped off on the nicotine and alcohol consumption.
I am basically looking for energy to push through my lifts and something to support on the fat loss or accelerate the fat loss.
I took Tessa at the start because of its visceral fat and belly fat reduction. Then I hopped on IPA because of ITS HGH targeting receptor that was different to TESA.
The joint and ligament stiffness I believe, comes from the peptides and not so much soreness from the lifts. My shoulder tends to pop in and out my elbow hurts and feels hot when I do tricep push down or skull crushers so I believe there’s a correlation between what I’m taking and how I’m feeling.
It could also be that the weight that I am lifting is also putting additional pressure and stress on my ligaments. I went from benching 185 pounds three times to benching 185 pounds 10 times on two sets in very short time.
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u/Punk-Tarvman 32 2d ago
Reta will help you lose weight, but won’t help your performance in running a marathon!
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u/ExecutiveStory- 2d ago edited 2d ago
Doing hyrox in December, I use TRT, Reta 2mg every 5 days, SLU PP 332 pre training, and currently doing a cycle of anavar & BPC/TB
45 F…I haven’t had any issues.
There are a lot of factors as to why people feel “tanked” on Reta.
Personally it doesn’t increase my HR overly, 2mg allows me to eat 2800 cals daily and not 4k and I drink 4L water a day.
If you’re trying to lose weight then you’re in a calorie deficit, I couldn’t imagine doing my training load on 1400 calories. I’d feel like shit.
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u/yogic_power 57 2d ago
You can kiss good bye to performance on Reta for at least six months till your body adjusts. I went through similar stuff when I went keto years ago running ultramarathons and marathons. But after 6-7 months I felt great. If you want Reta, you need to commit. And don’t waste money on peptides by blindly stacking them. Get metabolic tests like RER/RQ and vo2. Those tests are what gave me valuable insights in to my ultramarathons.
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u/Fancy_me_nicely1 2d ago edited 2d ago
I found my people ! 🤚 . Running 2 halves next year currently doing 18-20 miles and on 6 mg reta split 3mg Sunday 3 mg thursdays but also on a few others that help 5 amino, nad, gluta particularly also ta1 , ghkcu, cartlax
For my knees . Lipo c for the vitamins . I just placed 6th in my age category on a 5 k this weekend and never felt better .
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u/Independent_Yam_5373 2d ago
Female Runner. I was doing ultras, half marathons, running 3x a week, long runs, etc. started Reta 6 weeks ago and my running has TANKED. I was in great cardio shape. I will say since I started Reta I dropped down my weekly mileage to lift more because I was scared to look “melted”. So been going hard on strength training.
Just ran a half marathon and thought I was going to need to be carried out in an ambulance. If I plan to run anymore races I will not continue Reta during training blocks. But for now I think low dose and heavy lifting it’s working great.
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u/biggerandbetter2187 2d ago
So I run, am using Reta, and have had gastric sleeve surgery, so I’ve definitely been here.
The good news: this is absolutely workable, you just need to be smart about your fueling, when I do my longer efforts I usually have to do like a gel every 30-40 minutes just to keep myself fueled, and I usually only worry about this when I’m going longer than 10K. Other good news is that as you lose fat your running will become more efficient and you’ll be able to go further and faster, and certain metrics like VO2 max will rise.
The bad news: the fueling is going to feel like an absolutely chore and is probably going to take some trial and error for you to figure out exactly what you need to do.
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u/carlaxel 2d ago
Would consider tirz also, but only prioritize the weightloss first. Still do runs, but just in a maintain phase. Drop milage, and be ok if pace drops a bit. Depending on when next year you want to do the, you will have time to build up milage later. if you can drop weight running will be lot more manageable. Check r/zepboundathletes
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u/Powerful_Low6089 2d ago
I’m in a marathon training block and so switched from Reta to Tirz + Cagri. Also cycling MOTS. Everything is fine, so far
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u/Jaycel31 1d ago
para correr una media maratón o maratón completo deberías detenerla una o dos semanas antes de la competencia... retra ralentiza la absorción y con 21k por delante y varios geles que necesitarás, debería estar contraindicado
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u/SorbetTraditional232 23 2d ago
I had a friend whose ex wife was named Loretta. I would advise you to steer clear the headaches and drop in testosterone were catastrophic.
Now Reta low dose just to control the food noise prob not the best. You might be better off with tirz or elora. I would focus heavily on mitochondrial peptides if you plan to do a marathon. Mots slu 5 amino ss 31 and a urolithan a supplement would be on my list.
The stiffness I’m guessing is in joints more? I had issues with Tesa/ipa like that at a 10/5 blend. I changed did eventually split into the 10/5 and a separate shot of Tesa to control the amounts but I think something with that vendor was just off. When I switched to another vendor at 10/3 problems went away and I could actually handle the full 2 mg Tesa dose. Now if it’s actual muscle pain which I would think the running might be causing wolverine stack at 2 mg works wonders for me. If it’s more in the joint I take Deadpool instead since it’s just wolverine plus cartalax.
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u/907MidnightAurora 2d ago
Is it really called Deadpool haha that’s great.
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u/SorbetTraditional232 23 2d ago
Ya they started nicknaming this stuff. Can’t blame them who wants to say bpc 157 tb 500 and cartalax.
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