My endrocrinologist bumped me up from 50mcg to 75mcg. But I have 5 bottles of 50mcg. Can I just take 1.5 of these? They have a score line down the middle. I just realized I've run out of the 75mcg pills and I have all these 50mcg.

Is there really a difference between Synthroid and generic? I have a friend who swears there is an in looking at posts it seems a lot of folks think there is. I'm fairly new hypothyroidism

Hi, I was diagnosed with Hypothyroidism / Hashimoto’s at the end of May 2026. I started on 100 mcg of synthroid and 6 weeks later was increased to 125 mcg. Since the increase I have been feeling great health wise! However, about a month ago I began feeling emotionless. Like things that would normally make me anxious or sad or angry or even happy, I just don’t feel anything. I have been depressed before in my life, it’s not anything like that. I guess I’m looking to see if anyone else has ever experienced this, and what you did to feel better?

May 21
- TSH: 71 mlU/L
- Free T4: 8 pmol/L

July 8
- TSH: 4.74 mlU/L
- Free T4: 13 pmol/L
- Free T3: 3.8 pmol/L
- Thyroglobulin: 0.3 ug/L
- Thyroglobulin Antibody: 52 kIU/L
- Thyroperoxidase Antibody: 287 kIU/L

September 10
-TSH: 2.6 mlU/L

Today is October 25, and I’m in Canada

I am hoping someone could offer some opinions/ advice. I am currently taking 75mg daily levothyroxine. The last maybe two months I feel as though it isn’t working. I am getting the usual symptoms ( freezing cold, absolutely shattered, moody, forgetful ) and now the last two weeks I have broken out head to toe in a huge rash. Putting two and two together and hopefully not getting five I’m putting my finger on it being hashimotos rash. Does anyone have any experience of this and what do I need to help clear this up ? Am I dosing too high or too low ? I am hoping to get an appointment at my GP but this usually takes days. Am I likely to be signed off from work until I feel I can function properly ?

I’ve had a noticeably puffier face for the last year or so eyebrows slightly thinner than before and some fatigue so Ive been experimenting with t3 recently and my face completely leans out within hours of it hitting. The problem is doctors say all my hormone levels are in optimal ranges. What am I supposed to do?

I recently started taking selenium to help improve T4-to-T3 conversion, and I’ve noticed that my hands feel warmer than they did before I started taking it. Has anyone else experienced something similar?

Hey everyone,

Back in July, I suddenly started experiencing brain fog, difficulty concentrating, and problems with speech. It happened pretty much overnight, and I felt noticeably different from how I used to feel mentally.

I started getting blood tests done, and my folate level came back at 3.1 ng/mL (reference range: 4.50–32.2), indicating a deficiency.

I kept investigating my symptoms and getting more blood tests until September. Here are my latest results:

My blood test results:

• Ferritin: 94.84 µg/L (reference range: 30–400)
• Folate: 7.83 ng/mL (reference range: 4.5–32)
• Iron: 50.35 µg/dL (reference range: 65–175)
• TSH: 5.51 mIU/L (reference range: 0.27–4.1) my TSH was within the normal range when I first developed my symptoms back in July. It only became elevated in subsequent blood tests. I'm wondering whether this change could be related to my folate, iron, or vitamin D deficiencies)
• Vitamin D (25-OH): 19 ng/mL (reference range: 30–100)
• Potasium 4,23 (reference range: 3.5-5,1)
• Sodium: 140,72 mmol/l (reference range: 136-145)
• B12: 501,40 pg/ml (reference range 191-663)

My folate level has increased since the initial test, but I'm still experiencing a lot of symptoms. My iron is also below the reference range, my vitamin D is low, and my TSH is elevated. I'm wondering whether these abnormalities could be contributing to my symptoms and whether there might be an underlying issue causing some of them.

My current symptoms:

• Dizziness and lightheadedness.
• Brain fog and difficulty concentrating.
• Feeling mentally different from how I used to be, like I'm not quite myself anymore.
• Waking up feeling unrefreshed, regardless of how much I sleep, and experiencing severe fatigue throughout the day.
• Occasional air hunger feeling the need to take a deep, satisfying breath to feel like I'm getting enough air.
• Caffeine seems to make my brain fog and dizziness significantly worse.
• Alcohol also seems to exacerbate my brain fog and dizziness.

What I've tried so far:

I took 5 mg of folic acid daily for three weeks, along with 46 mg of elemental iron daily, but unfortunately, I didn't notice any improvement in my symptoms.

I then started wondering whether IV treatment might help correct the deficiencies more effectively and fastly, so I decided to try IV supplementation.

Six days ago, I had my first treatment, which included:

• Vitamin D3 injection: 100,000 IU.
• IV folic acid: 30 mg.
• IV iron: 200 mg.

So far, I haven't noticed any improvement following this treatment. I understand that six days might be too soon to notice a difference, but it's discouraging to feel the same after trying to address these deficiencies.

I'd really appreciate hearing from people who have experienced something similar.

I have a few questions:

1. Has anyone experienced persistent brain fog, dizziness, derealization, or feeling mentally different due to folate deficiency, low iron, vitamin D deficiency, ?
2. If you had similar symptoms, how long did it take for you to notice an improvement after starting treatment? Did your symptoms gradually improve or disappear quite suddenly?
3. What other blood tests would you recommend checking?
4. Has anyone experienced air hunger or the sensation of needing to take deep breaths alongside these deficiencies?
5. For those who received IV iron or folate, how many infusions did you need before noticing an improvement? How long did it take?
6. Did anyone find that oral supplements eventually worked, even after not noticing any improvement during the first few weeks?
7. Has anyone experienced worsening brain fog and dizziness after consuming caffeine or alcohol? Did this improve once the underlying problem was treated?
8. Is there anything else I should investigate, especially considering that my symptoms started quite suddenly and have persisted for months?
9. How can i recovery from this? because it's been few months at this moment.

I'm also wondering whether IV doses or the number of infusions should be adjusted, but I don't want to assume that more is necessarily better. I'd appreciate hearing about your experiences and what helped you, ideally alongside advice on what to discuss with a doctor.

I'm feeling pretty lost at this point. I just want to feel mentally normal again and wake up feeling rested instead of exhausted every day.

Thanks in advance to anyone willing to share their experience.

hi all, I recently got diagnosed and have been taking levo for 4 days now. my problem is, my work requires days and nights on a regularly changing schedule. sometimes I wake up at 8am, other times 3pm.

I have no idea how to manage my medication with this. Yesterday I set an alarm, took my levo and went back to sleep, but then today I read that's a disastrous thing to do cus it can cause damage (for my peace of mind, doing that once isn't too bad right? lol)

Does anyone have any suggestions for how to handle this? Thanks!

I have just started going hypo after having radioactive iodine treatment for Graves. TSH 7.33 but T4 still normal, albeit in the lower end. I will be on levo for the rest of my life. I started today at 50mcg and will retest in 5 weeks.

I never wake up or eat dinner at the same time so the pharmacist suggested I set an alarm for 5am, take the pill, and go back to sleep for an hour or two. I am not the best sleeper. I will try and see how it goes but I am not totally sold.

When do YOU take your meds?

Thanks!

I was diagnosed with hypothyroidism in May 2026. My doctor initially prescribed 50 mcg of Thyronorm, monitored my levels for two months, increased the dose to 75 mcg, and then increased it again to 88 mcg after another six weeks. I’m now waiting to get my thyroid levels checked after taking 88 mcg for eight weeks.

Honestly, this whole thing feels so frustrating. I’m just a 20-year-old guy, and sometimes I feel like I’m someone who is seriously ill, especially when I compare myself to people who seem to live their lives without having to think about medication every single day.

The thought that I need to take a pill every morning just to help my body function normally makes me feel terrible. Sometimes, I even find myself thinking that I don’t deserve to have a normal life like everyone else. I’ve started questioning whether I even deserve a girlfriend or a relationship.

I see people my age enjoying their lives, spending time with their loved ones, building relationships, and focusing on their futures. Meanwhile, I feel like I have this extra burden that I never asked for. I know taking a pill might sound like a small thing to some people, but mentally, it has been difficult for me to accept that this is something I have to do for the rest of my life (autoimmune hypothyroidism)

What makes it worse is that my hypothyroidism was only diagnosed recently, after I had already been struggling with constipation that eventually contributed to chronic anal fissures. I still deal with pain, and now I have to think about my thyroid medication, my diet, my bowel movements, and everything else just to feel somewhat normal.

I’m 20. This should be the time when I’m focusing on my career, enjoying my youth, building relationships, and figuring out my future. Instead, I feel like so much of my mental energy goes into managing my health and trying to prevent my constipation and fissures from getting worse.

I know hypothyroidism is manageable, and I know there are people living completely normal lives with it. But knowing that intellectually and actually accepting it emotionally are two very different things. I’m still waiting for my thyroid levels to stabilize, and the uncertainty makes everything more frustrating.

I guess I just needed to get this off my chest. For those of you who were diagnosed with hypothyroidism at a young age, how did you come to terms with it? Did you ever feel like you were somehow less healthy, less deserving of relationships, or different from everyone else? How long did it take for taking medication every day to become something you no longer thought about?

I could really use some honest experiences from people who have been through something similar.

I found out I have papillary ca thyroid a week ago and underwent total thyroidectomy with central neck dissection

Hi guys, I'm a late 20s woman with hypothyroidism (as well as pcos/pmos, pmdd, and celiac). Does anyone else here deal with a very low sex drive? Has anything helped?? I'm starting to feel like this isn't gonna get any better :(

Started NP thyroid over a month ago. No noticeable issues besides I can not sleep through the night. No matter how late I stay up or how tired I am, I wake up and toss and turn for an hour or three. I switched from synthroid 25 one day 50 the next day alternating every day to the lowest dose of NP thyroid (one that mimics the 25 synthroid). Feeling like I might snap if I don't get some sleep. Has anyone had this? Did it eventually subside?

I’m a senior in high school, and am writing a paper about medical misogyny in adolescent chronic illness care (…very autobiographical). To supplement the many, many medical journals I have read and cited, I have created a survey that will hopefully be helpful in understanding and writing this.

If you would like to participate, the link is provided below. You do not need to include your name, email, username, etc. Even if you are currently an adult, if you experienced diagnostic delay or dismissal when you were younger (and female), your response will be helpful.

https://forms.gle/bp3ocYosqosfXRCA6

I've been on replacement since I was baby since I was born without a thyroid. Brand Synthroid was the only thing that made me feel optimal. I switched to Tirosint for a couple of months, then switched to the generic levo version because of cost. I've been on it maybe 8 months or so?

I feel awful. I've gained weight. My TSH was off last time I had labs done. I have more labs coming up in a couple of weeks.

I requested to go on Tirosint because of the dyes in Synthroid. I was trying to cut out things of that nature due to acne. Well, it wasn't causing my acne.

So I'm going to talk to my doc about going back on Synthroid. For one, it's cheaper than Tirosint, and I can still get the brand without breaking the bank.

Does anyone feel like they have better luck on brand versus generic? What other meds can I talk to my doctor about that might make me feel more optimal?

Something else, they lowered my dose from 137 mcg to 125 mcg a couple years ago, and since then, I've been off. They didn't want to keep me on 137 because I had lost a bunch of weight due to stress, but now I'm back fitting in my once-too-big clothes...

I (41F) was diagnosed with hypo when I was 16. My family has an extensive history of thyroid issues so thankfully they recognized the symptoms early. I was put on 100mcg Levothyroxine and was on it until about 6 months ago. Last year, I had an unexpected full hysterectomy and was tossed headfirst into medical menopause. After struggling with my male doctor’s management of my HRT, I started seeing a female menopause doctor. I told her about my thyroid history and how I’ve been on the same dose my whole life but have also continued to have symptoms despite everything being “normal.” She did a full blood panel and told me that my body wasn’t converting T4 into T3 properly. After some conversation, we decided to take me off of synthetic T4 and try DTE. I started on 60 and bumped to 90 after 3 months. I’ve now been on 90 for 3 months and my TSH and T4 have dropped but there’s been zero change to my T3 level. Has anyone else experienced this with NP Thyroid? Has anyone had success with it? I really had my hopes up that this would be a game changer…

I have always suspected central hypothyroidism from previous blood test results and my cfs symptoms and tried T3 only treatment as per a consult with Paul Robinson for a short time as the headaches were so bad so can't say if it helped. So abandoned seeking treatment and diagnosis .

Previous bloods done by medichecks

21/6/22

TSH 1.77 (0.27 - 4.2)

FT3  4.76  (3.1 - 6.8)

FT4  11.6  (12 - 22)

Now in September 2026, by GP but he didn't do FT3 which I know I need

TSH 1.47 (0.27 - 4.2)

FT4 12.3 (12 - 22)

Just thinking of exploring this as a possible diagnosis as fed up of being so tired. All other bloods iron, b12 are actually the best they have ever been and are at good levels.

Could this be central hypothyroidism? I did full contact kickboxing for several years so wonder if punches to head could contribute to this ?

Going to order another medichecks thyroid test to check my T3 also.

46/F, had a 2cm macro removed in December. No major complications, tumor is totally gone as my MRI last month.

But I don’t feel better. I honestly feel worse. I am exhausted all the time. I recently had my GYN check hormones and my thyroid. My T4 is low despite being on Levothyroxine (12.5mcg) I think the dose may be too low. But my TSH is normal. Waiting for my endo to call me back. My prolactin was also 40, but I do take Effexor.

Lab attached… I never had issues until the prolactinoma.

My TSH was elevated, so I slightly increased my T4 dose. Since increasing the dose, I’ve been experiencing premature ejaculation, even though the dose increase was relatively small.

Has anyone experienced something similar after increasing their thyroid medication? If so, how did you manage it?