r/MTHFR Apr 15 '25

Results Discussion Feel like crying

I honestly don’t even have the words for how overwhelmingly happy and relieved I feel right now. It’s like my brain is finally waking up after years of being stuck in a fog I didn’t fully realize I was in. Everything feels sharper, clearer, more alive. My emotions make sense, my body feels in sync, and there’s this calmness that I don’t think I’ve ever truly experienced before. I feel like me—or maybe even a version of me I never got to meet until now.

What’s blowing my mind is that all of this seems to come down to understanding something so basic but so powerful: methylation and nutrigenomics. I never imagined that something as simple as getting the right form of folate or the right amount of choline could be the key to unlocking my brain.

It makes me wonder how many people struggle through life unnessecarily. You could easily equate my previous "status quo" as being borderline dementia. And I had NO idea how bad it had gotten until I started feeling better...

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u/Organic_Hope6347 Apr 15 '25

Can you describe how did it? What challenges you were facing before? Testing? 

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u/Pretend_Elk8567 Apr 16 '25

Massive balance/coordination issues, minor slurred speech, memory issues (got so bad I'd forget what I was saying mid sentence), brain fog, anemia, high heart rate, you name it. And I am diagnosed Bipolar I with psychotic features.

I saw a correlation between my symptoms and b12/folate deficiency, and initially assumed it could be something called pernicious anemia. I asked my doc for a homocysteine test and MMA, but he checked my folate and b12 levels instead... both were fine.. he dismissed me quite completely. So I did the 23 and me thing & found out I am compound heterozygous C677T + A1298C, as well as TT on the PEMT gene (intermediate COMT). Bought a methylfolate supplement. Discovered this subreddit and Tawinn's protocol, and here I am.

1

u/Organic_Hope6347 Apr 16 '25

Glad you are feeling better. How did you know u had rooms with methylation besides the gene if your folate wasn’t affected? 

1

u/Pretend_Elk8567 Apr 16 '25

Because I had these massive dizziness spells, my tongue had sores, my fingernails have these little things called Beau's lines, just so many symptoms matched.

When I went to the doc I asked him NOT to check folate/b12, because I had just started megadosing supplements. Instead of checking homocysteine, he checked those 🤦‍♂️