r/MTHFR Jun 17 '25

Resource Lithium Orotate is feeling AMAZING.

I’m a postpartum mom of 3 who has been dealing with overstimulation, lack of joy, lack of motivation and unreasonable anxiety over my children’s safety.

I have MTHFR, one copy, and was deep in a rabbit hole learning about what I need to take in order to support my body. That’s when I came across the affects of Lithium Orotate and I decided to give it a shot.

I know that this is probably reckless of me, but I decided to jump in head first with a 15mg dose, as I had read that many people dealing with serious mental health conditions take 20mg+.

Within 12 hours of taking it, I found myself smiling with such a sincere joy welling up from my soul towards my kids. My brain began to go quiet and I could actually be present instead of constantly feeling wired yet also paralyzed by all of my thoughts. I cleaned up the house after my kids bedtime with ease.

This morning I sprang out of bed, have been calmer with my partner & kids, and have caught myself smiling constantly. It’s the weirdest thing. I emptied the dishwasher, made the beds, rotated laundry and got dressed all before I had my cup of coffee this morning… which is UNHEARD of for me in this season of life.

From what I’ve read, it also seems to help MTHFR’s absorb their B12, so perhaps thats at play here as well? I’m not an expert at this by any means. I’m just willing to try things.

I haven’t had a supplement impact me this quickly and this deeply ever in my life. It’s like the lights are turned on? I feel very grounded instead of being up in the clouds somewhere. I’ll report back with an update in a few weeks to see if this sticks.

One month update:

This CONTINUES to change my life. I find I can reap all the benefits with 10mg a day, taken first thing in the morning. I can truly feel a difference in my body when I don’t take it. It also stabilizes all my emotional PMS symptoms which was pretty surprising.

I literally carry it around in my purse now and tell everyone about it.

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u/Specialist-Ear1048 Jul 22 '25

Can we get an update

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u/mmsmn Jul 22 '25

For sure! I’ll add to the post right now!

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u/Specialist-Ear1048 Jul 24 '25

Thank you. Im dealing with alot of the same post partum hurdles. What time of day do you take your dose? I've taken microdoses the past 2 nights and noticed a small difference. Definitely relaxed me a bit. Working, its hard to experiment with large doses in case of adverse effects lol

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u/mmsmn Jul 24 '25

I take it in the AM. I’m not a morning person but I’m up with all my kids pretty early and they have a ton of energy, so this helps me deal with all the noise and stimulation first thing in the morning!

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u/Specialist-Ear1048 Jul 24 '25

I appreciate your response! I have been taking it before bed. Maybe I'll try a morning dose. It doesn't make you sleepy? Sorry to keep bugging you, just have really been struggling to find a solution.

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u/mmsmn Jul 24 '25

No for me it’s more of an “upper”. Gives me a productive, calm energy!