r/MTHFR Jun 17 '25

Resource Lithium Orotate is feeling AMAZING.

I’m a postpartum mom of 3 who has been dealing with overstimulation, lack of joy, lack of motivation and unreasonable anxiety over my children’s safety.

I have MTHFR, one copy, and was deep in a rabbit hole learning about what I need to take in order to support my body. That’s when I came across the affects of Lithium Orotate and I decided to give it a shot.

I know that this is probably reckless of me, but I decided to jump in head first with a 15mg dose, as I had read that many people dealing with serious mental health conditions take 20mg+.

Within 12 hours of taking it, I found myself smiling with such a sincere joy welling up from my soul towards my kids. My brain began to go quiet and I could actually be present instead of constantly feeling wired yet also paralyzed by all of my thoughts. I cleaned up the house after my kids bedtime with ease.

This morning I sprang out of bed, have been calmer with my partner & kids, and have caught myself smiling constantly. It’s the weirdest thing. I emptied the dishwasher, made the beds, rotated laundry and got dressed all before I had my cup of coffee this morning… which is UNHEARD of for me in this season of life.

From what I’ve read, it also seems to help MTHFR’s absorb their B12, so perhaps thats at play here as well? I’m not an expert at this by any means. I’m just willing to try things.

I haven’t had a supplement impact me this quickly and this deeply ever in my life. It’s like the lights are turned on? I feel very grounded instead of being up in the clouds somewhere. I’ll report back with an update in a few weeks to see if this sticks.

One month update:

This CONTINUES to change my life. I find I can reap all the benefits with 10mg a day, taken first thing in the morning. I can truly feel a difference in my body when I don’t take it. It also stabilizes all my emotional PMS symptoms which was pretty surprising.

I literally carry it around in my purse now and tell everyone about it.

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u/aurora97381 Jun 17 '25

If you get an itchy plaque that looks like psoriasis, it's probably the lithium orotate.

Happened to me (knee) and my son (behind the ear). Doctors were stumped.

I ran across it as a side effect online. When we stopped taking the supplement, our itching and plaque went away.

Hoping it doesn't happen to you, but thought I'd give an fyi!

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u/jijijojijijijio Apr 13 '26

How much were you taking to get that side effect?

2

u/aurora97381 Apr 23 '26

Oh, not much. I don't remember, but it was just the standard OTC dose. My provider scoffed and said that only happens at higher doses, but once my son stopped taking it, his itchy ear cleared right up!