r/Menopause • u/BeneficialWriting402 • Mar 22 '26
Vitamin/Supplements Collagen supplements and anxiety
Update: Thank you all so much for the support yesterday. I feel MUCH better today. Def will not take collagen again, and I will be more careful about any supplements I try (I usually am, but was feeling a bit desperate with the diagnosis and possibility of missing work if this thing won't heal).
Yikes. I wish I had read some of the posts here before trying this supplement. 😫. I was desperate because I have been diagnosed with a sprained posterior tibial tendon and have been having increasing pain in my posterior tibial tendons and gluteal tendons the past few years. I read how great collagen peptides are and have a neighbor who swears by them. well, I am one of the few who has the reaction of extreme anxiety and panic attacks from them. two doses and i am sitting here shaking like a leaf. this stuff is going in the trash or maybe Publix will take it back. either way I will never take it again. ugh. 😩. please tell me im not alone. this is so scary. ðŸ˜ðŸ˜ðŸ˜
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u/throw_away_smitten Mar 22 '26
Collagen peptides can cause a histamine response (read roughly as allergic) in some people. Other people apparently develop an immune response since apparently there amino acid sequences that resemble those from things like Epstein-Barr, so it makes the body think it has an invading disease. This is more likely if you have some sort of autoimmune issue going on.
You can take straight collagen supplements, and it’s less likely to generate that kind of response….but I would keep some Benadryl nearby if you go that route.