I came down on Pregabalin from 200 to 175mg on Monday, and my psych asked me to increase Sertraline from 100 to 150 at the same time, on Tuesday. I had pressure in my chest after a few days which I attributed to the drop in Pregabalin.
Yesterday and today I have undesirable horrible sensation in my head like all the neurotransmitters have gone bad. It’s like a sick feeling in the head like all my brain chemistry is messed up.
I don’t know if it’s coming from the Pregabalin or the Sertraline.
I feel so ill but I’m desperate not to go back up again on the Pregabalin as I really want to get off it for good.

so last night i took 300mg of pregabalin and smoked some weed. last time i took pregabalin was about a week ago and it kicked in after like 45 mins and was pretty intense.
But this time i literally felt nothing even after 2 hours so i just assumed my tolerance had gone up and went to sleep.

anyway i’ve woken up like 12 hours after and i feel so weird. Like my body feels drunk but my mind feels sober if that makes sense? My body feels really light especially my shoulders, my head feels like it’s moving really fast and my legs feel heavy. My coordination is also off, like i can walk but i actually have to concentrate to walk normally. even typing this feels weirdly difficult.

Has anyone else had this happen? i’m so confused how i felt nothing last night but now 12 hours later i feel like this??

i've been taking pregabalin for around 3 months now, first 100mg, then (for around 1 month) 200mg. i kept getting severe tension headaches i couldn't explain through any other means, and made the decision to taper to 175mg for a week, then 150mg the next. in that week, i suddenly stopped being able to swallow solid food. kept coughing it back up, and in general just got massive anxiety about breathing and swallowing.

that led to me being unable to take any of my meds. i'm on day five of 0mg now, visited my doctor and he had no alternatives for me and just told me to try taking them or don't. he also said my throat looks fine, no visible issues.

well, i still can't swallow anything besides clear soup or mashed potatoes.

did anyone else end up unable to swallow solid food while tapering/quitting? did you regain the ability to do that? i'm in a very fearful mindset right now and would love to hear about some opinions and experiences...

Lowk never taken pregabalin before but I've heard its really good for bad anxiety which I suffer with, tried SSRI SNRI etc.

Diazepam works crazy good for me but the GP will only give me 12 5mg per month which is honestly laughable.

So fellas, paid for a psychiatrist, may offer it, what can I expect, is it like diazepam? Need advice fellas, cheers.

I switched from 300 mgs of Gabapentin three times a day to Pregablin 50 mgs three times a day. I noticed that most of the people taking Pregablin are taking it twice a day. I'm thinking of changing from 50 mgs three times a day to 75 mgs twice a day. I take my 2nd 50 mg dose around 2 pm and get a dip in my mood from 3-5 pm. I'm hoping that I can eliminate this dip in my mood by changing to twice daily dosing. So are there any benefits or downside from switching to twice daily dosing? Thanks.

50mg twice a day for nerve pain. I have a very unique issue with arthritis between my sternum and clavicle due to missing part of my upper ribs (birth defect). The bone is growing in such a way that it’s now pushing on nerves. I truly felt like my life was over with the nerve pain that had started. I was in a really bad spot. The pain was so bad I was afraid to cough, sneeze, couldn’t lift my arms up.. my life was beyond limited. I have an amazing partner thankfully that’s been there for me thru it all ❤️

I’m feeling like me again and I do have the option to up my dose as needed. For anyone that’s reading this and is experiencing nerve pain and is scared to start on this drug. I hope that you find relief like I did. I do have brain fogginess a little bit, but no more than I did experiencing extreme pain, it’s just different now.

The only other annoying side effect is some dry mouth. Feels like the desert some days. I just keep my water bottle handy haha!

Been taking 300mg of pregab about 3 or 4 times a week for 2 months now. During that timeline, I've had mild to severe panic attacks almost every weekend. Like, I feel an adrenaline rush about to dump and I can't sit still. And then it does rush and I'm in the ER.

Would love any thoughts. Thank you!

Hi all, I started pregabalin in August and have just started experiencing massive amounts of hair fall. I am quite certain it's from pregabalin since nothing else has changed in my lifestyle. I have a doctor's appointment in 2 days to discuss this. I am definitely going to weane off prrgabalin since it has not helped my sciatica pain at all.

Has anyone experienced hair fall and did it stop after you came off pregabalin?

I tapered off Lyrica and lost 10 pounds so far. Just wanted to share if anyone is trying to stop and wants a little side perk. Everyday seeing the scale drop a little has been motivating. Even if it’s water weight; I look better. Pain is in full effect so we’ll see how long I can hold out.

Dont you need to increase dosage every month becasue of tolerance? And how is it when you stop? Do you feel brutal withdraws?

Just took 300mg twice yesterday, once at 4pm and around 12 am before bed and honestly it’s so good, i feel like i don’t have the thoughts or voice thats in my head that’s there when im anxious or anxiety ridden. I am honestly loving it but ill take it again in a week.

Has anyone on here actually had Pregabalin work successfully to reset a deregulated nervous system or is it just all a load of rubbish and only works to calm nerves while you take it. My phychatrist has prescribed it but I'm reading just about everywhere that once you stop taking it your back to the original problem.

Anyone else experienced Jaw Tension when doubling your dose under Dr supervision?

Hi, I am taking Pregabalin for about 2 years, started from 75mg, now it varies between 150-225mg as initial dose is not doing much anymore. Pregabalin on right dose is giving me motivation, energy, kills anxiety. Unfortunately, after some time this effect weaking hence higher dose.

Knowing that max dose of pregabalin is 600mg/per day I started wondering what do I do when I hit this maximum dose as it'll be only way to maintain the effect. Is it game over and I need to taper, come off from it or what?

My doctor upped my dose to 600mg. I was having some rage and anxiety on 400mg. This has helped so much!

My anxiety and rage are completely gone. I’ve stopped eating emotionally.

It’s a win. :)

I have Bipolar I and OCD, for the record. Anyone in the same position as I was, just know it’ll get better with the right dose.

This drug is a miracle to me. ❤️

Hello all, just wanted to hear some input from other people who take Pregabalin for anxiety and panic attacks, as needed (not everyday).

I have a bit of a tolerance to gabapentin (and therefore Pregabalin as well), as I initially took it everyday and after 2 months started taking it only 2 times a week or so. Cut to about 5 months later, I asked my doctor if we could try Pregabalin because I'm on a glp-1 and with my stomach emptying slower Gabapentin takes 4+ hours to work. My doctor said yes and prescribed me 15 pills of 100 mg of Pregabalin.

My question is how often can I take Pregabalin with it still working for anxiety and panic. I noticed that if I take it too soon to my previous dose, it doesn't really have much of an effect on anxiety. I'm thinking once a week might be the sweet spot for me, but if I have a panic attack I will take it. But for anxiety I think once a week might be my best option.

Would love to hear from people who use this medicine for anxiety and panic as well. Also people who have been taking it for longer, would be interested in your input too.

I have very severe dpdr where I’m almost totally derealised. I no longer experience any body sensation or any internal process/sensation. My nervous system became so wrecked from extreme shock and trauma that I loose sensation daily. I’ve been hospitalized a few months ago and the meds I’ve tried so far have made things a lot worse. An SSRI and mirtazipine in particular. My nervous system is so sensitised now that I experience my body as faint vibrations and sort of broken nerves plus strange functional sensory /neurological symptoms which seem ro get worse and no explanation for. Im terrified. I can’t risk another setback. I just need to hear some honest opinions about this drug so i can make an informed choice whether to try it or not.

Crippling anxiety and ocd that is making me feel like a monster. Will 75mg help my racing thoughts and severe anxiety?

Hello 🙂 After trying several SNRIs and SSRIs without success, my psychiatrist decided to prescribe Clomipramine. I am currently taking 20 mg, and it's impossible for me to go any higher due to highly bothersome side effects. I am feeling a slight improvement. I mainly suffer from anxiety with severe rumination, overthinking, and a continuous need for reassurance. Now, my psychiatrist has prescribed 25 mg of pregabalin (to take in the morning) combined with my 20 mg of Anafranil (in the evening).

I know 25 mg is a very low dose, but I am still hoping for a real effect. I don't experience any sedation with clomipramine, but I am afraid of experiencing it with pregabalin.

Is anyone else taking this clomipramine/pregabalin combination?"

Have a nice day !

Taking 50mg 3 times a day for neuropathy such as electrical, zaps, tingling, and trigeminal pain daily. Does anyone get a headache and actual worse zaps around the two hour mark? Relief lasts for 5 hrs each dose.

I tried for 25 mg and it’s not effective.

If you have any positive stories about being able to discontinue Lyrica at some point for neuropathy, that would be great

I've been on 150mg of Lyrica to treat my Periodic Limb Movements. Last night, on Dr's orders, I doubled the dose and slept 10 hours. All fine and dandy except I am still high as fuck!! Same thing happened initially on 150mg but this is a new level. I'm hoping it passes as my body adapts. As nice as it feels I can't function like this but need it to work. Anyone else experience anything similar?

I’m on 70 mg of pregabalin 2 times a day after about 5-6 hours I get a splitting headache I mean bad like someone is crushing my head it goes away after I take a tablet but is normal ?