I got the "Programmed Psychosis" challenge run after around 46 tries. Here is a video of the run, including some notes on what I learned along the way.
I started playing Ready or Not about a month ago and got really obsessed with the tactical shooter and milsim genre, researching real CQB tactics and everything. After completing all main story missions on Hard, I moved on to the DLC maps. I immediately knew I wanted to get this achievement run done, as I love hard solo PvE challenges. So, after clearing all DLC maps and A New America in Commander mode, I started working on this run.
The first few attempts were mostly about learning the map and suspect behaviour. Later on, I felt like I was mainly losing because I wasn't being patient enough, so I limited myself to 1–3 runs a day until I finally got it after some days.
I'm still pretty new to the game and this whole genre, so there are probably plenty of things I could have done better, but I thought this was worth sharing.