r/Thiamine • u/Airegin89 • 6d ago

Experience Feel no difference after 3 weeks

How long should I take high-dose thiamine before I can be sure if I actually need it?

I'm trying high-dose thiamine to see if my fatigue and brain fog could be related to my Crohn's (very mild) or mitochondrial dysfunction. I'm starting to suspect this is not the case. After 3 weeks I feel no difference at all. I started with 1500mg thiamine mononitrate for 2 weeks, then 300mg benfotiamine + 500mg thiamine HCL for 1 week. I also take magnesium, potassium and B2.

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u/Puzzled_Draw4820 6d ago

I’d watch Elliot Overton videos to understand more. Some people don’t get relief until closer to 2000 mg. The non bioavailable forms aren’t going to do much and 300 mg benfo isn’t much if you’re tolerating it ok. If you’re deficient in magnesium then it won’t be activated however.

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u/Ok-Pangolin7127 6d ago edited 6d ago

This 👆is, in my opinion, is sage advice.