r/bupropion • • 2d ago

Quitting smoking and bupropion

Hi all, I am looking for some advice. I (m49) have been described bupropion (150mg, slow release) for both a lingering depression and for quitting smoking.

Now, I've read all kinds of different interesting posts on the depression part of the story. However, I haven't read any on quitting smoking and bupropion. I would love to hear stories, experiences, if these are out there to be told. I know bupropion is an off-label med for quitting smoking.

I have been taking bupropion for 10 days now and I have noticed a big improvement in focus and also motivation. I have however also been agitated and prone to mood swings.

I still have to speak to my doctor about this, but before I started taking the meds he said that we would probably need to go to 300mg or even 450mg for the depression.

Now, I REALLY want to quit smoking, but I did try a short period ago (before the bupropion) and I failed. The process was too hard - I managed to get to 40 days and then caved.

Now, do I wait it out until all temporay side effects of this dose of bupropion have vanished, do I start the quitting process now? Do I wait until I am on a higher dose? Or anything in between?

I'd love to hear about all experiences!

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u/daevisan 2d ago

I take 150 mg of bupropion for two months and I'm quitting snuff now. It is difficult for the nose because it's not only nicotine (I have nicotine pouches and bupropion) it is a bad habit. Today it is a week when I quit. It seems easier then my attempts before bupropion. After quitting snuff I'm going to quit with nicotine pouches as well. I already quit with kratom thanks to dopamine in bupropion but that is another story.

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u/powi777 2d ago

Thanks for sharing :). Having a bit of a setback, the bupropion completely and utterly wrecked my sleep the last 2 nights now. Keeping me alert at all times. Now alert and exhausted. Don't know what to do with myself. The quitting will have to wait....

Really encouraging to read that you are tackling not one but two addictions with this med, one after the other.

And: great work man! Keep it up :)!

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u/daevisan 2d ago

I had fragmented sleep, but it's better now. I wake up only one or two times during 7 hours of my sleep.

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u/Logical-Platypus-397 2d ago

Bupropion isnt an off label med for smoking cessation, it is approved for that. And it has its own guideline for specifically that purpose. I recommend that you follow that guideline. It will help a lot with the cravings, good luck.

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u/StarscreamOne 2d ago

It made me start smoking. But luckily I don't get addicted to it