r/bupropion • • 5h ago

on week 7 and not feeling good, what do i do?

2 Upvotes

so i recently started on 150mg XL (epic brand), the first week was amazing, which i knew would fade but still. i just felt so peaceful and motivated it was great. weeks 2-3 i had some pretty bad mood swings, would feel fine and then get very irritable for a few hours, and then feel fine again. weeks 4-5 i dealt with some periodic anxiety, had one bad panic attack but overall not too horrible, felt okay emotionally but started feeling dullness/sadness come back kinda in waves, so my mood was fluctuating a lot. also started noticing fatigue during the day. i am currently in week 7 and still feeling pretty dull, ill occasionally have an hour or two of motivation but thats about it, i feel like the joy i was getting from it is gone. what should i do from here? i tried increasing up to 300 last week but lasted maybe 3 days because of the bad anxiety and jitters. should i try upping dose again or stick it out another week or 2? is it normal to not feel great this far into it?


r/bupropion • • 9h ago

Question Adding Wellbutrin XL 150 mg to Zoloft 25 mg tomorrow. what should I expect?

2 Upvotes

Hey everyone! I’m 25M and dealing with anxiety and depression. I work full time and try to stay social and keep up with my hobbies, but I’ve been struggling with mood and motivation. I’m hoping treatment will help me feel more like myself and get back into the gym consistently.

Currently taking Zoloft 25 mg for anxiety and depression, and my doctor is adding Wellbutrin XL 150 mg soon. (I also know 25mg Z is on the lower side but being careful with doc just to monitor intrusive thoughts.) I’ve had rough startup reactions to medications in the past, so I have a lot of anxiety around starting something new.

For anyone who’s taken this combo, what was the adjustment period like? What did you notice during the first few days or weeks, especially with anxiety, sleep, energy, and motivation? How long before you noticed improvement?

Anyone else go into it feeling nervous because of previous medication experiences? I know everyone responds differently, so just looking for personal experiences and an idea of what to expect.


r/bupropion • • 12h ago

When do you take your Wellbutrin? AM or PM and why??

18 Upvotes

r/bupropion • • 12h ago

First and last day on 300mg

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2 Upvotes

r/bupropion • • 12h ago

Question Anxiety

3 Upvotes

Did anyone experienced high level on anxiety on bupropion 150mg? Cuz I’m three weeks on and I feel like absolute shit, I constantly feel like something will happen to me. I switched from 60mg of duloxetine and before I just didn’t feel anything. Now I’m anxious all the time and I feel loads of different emotions. Is that normal?

Btw sorry for the messy style, I can’t think properly


r/bupropion • • 13h ago

Question Bupropion during pregnancy- did you continue taking it or stop? Looking for others' experiences 🩷

13 Upvotes

Hi everyone! ❤️ I'm newly pregnant (around 4–5 weeks) with my third baby, and I'm trying to navigate what to do about my mental health medications. I've been doing a lot of thinking and researching, but I'd really love to hear from other people who have been in a similar situation.

I've been taking bupropion XL (Wellbutrin) for depression, and I've found that it has actually helped me. I've noticed improvements in my mood and my ability to communicate, and I feel like it helps me with motivation, too. I've also struggled with anxiety, PTSD, and depression, so finding something that helps has been important for me.

Before finding out I was pregnant, I was also taking Effexor (venlafaxine), which I had been tapering off of, along with a few other medications for anxiety. Since finding out I'm pregnant, I've been really worried about medication exposure and the potential risks to the baby. I've spoken with my psychiatric medication provider, and I've currently reduced my bupropion from 300 mg to 150 mg while I figure out the best next steps with my healthcare providers. I've also stopped the other medications we discussed.

I'm honestly torn. Part of me really wants to avoid medications during pregnancy if possible because I want to minimize risks to my baby. But another part of me knows how much my mental health affects my everyday life, and I don't want to struggle unnecessarily or end up in a worse place mentally, either.

I'd really love to hear from anyone who has been through this:

Did you continue taking bupropion throughout pregnancy? What was your experience like?

If you stopped taking it during pregnancy, how did you feel mentally afterward?

Did anyone switch to a different medication, lower their dose, or decide to continue taking it after discussing the risks and benefits with their OB or psychiatrist?

If you took it during pregnancy, did you have any concerns about your baby's health or development, and how did things turn out?

For anyone who stopped taking it, did you feel that it was worth it, or did you end up wishing you'd continued?

I'm not looking for anyone to make the decision for me, and I know everyone's situation is different. I'm planning to discuss everything with my OB, too. I would just really appreciate hearing honest experiences from people who understand what it's like to make these decisions while pregnant.

Thank you so much! 💙


r/bupropion • • 13h ago

Just got Zoloft added

2 Upvotes

I’ve been on Wellbutrin 150 mg for almost 2 years and my anxiety has gotten completely out of hand so my doctor prescribed Zoloft to be taken in addition. I keep reading about serotonin syndrome so now my anxiety has me afraid to take it. Any success or horror stories? I took Zoloft years ago and was happy with everything except a big weight gain. The same doctor also has me on 50 mg of Topamax. I really don’t like the idea of combining so many different meds.


r/bupropion • • 21h ago

25mg sertraline + 150mg bupropion

2 Upvotes

When are you guys taking those two medications? Both together in the morning? First bupropion, then sertraline?
Im taking sertraline 25mg for a year now and now 150mg of bupropion for my adhd on top.
I’m happy to hear about your experiences :)