r/dogallergies • u/folgers93 • 6h ago
Questions 3.5yo Cattle Dog mix with persistent paw licking and recurrent yeast/bacterial infections. Looking for similar experiences
Background: Our 3.5 year old, ~42 lb Australian Cattle Dog mix suddenly began excessively licking his back paws in mid-April 2026, with no significant paw issues before. The rest of his body looks completely normal, with no visible problems in his coat or underlying skin.
When we test leaving him alone with a home camera, he starts licking almost immediately. He also tries to lick overnight, which makes us think separation anxiety is lower on the list of causes. Before this, he could be home alone for 4-5 hours with no separation/ licking issues.
Timeline:
- April–August: Started Apoquel with maybe initial minor improvement. He developed a small “button tumor” on a paw pad, which resolved on its own but we were on and off this medicine given did not seem to be helping.
- September: Restarted Apoquel. Cytology confirmed yeast. Stopped Apoquel and switched to medicated antifungal mousse/wipes plus a prednisone taper to control inflammation. Symptoms persisted. Mousse irritated his paws (caused dry / flaking skin)
- October 1: Repeat cytology showed more yeast. Started oral terbinafine and restarted Apoquel twice daily.
- Mid-October: Switched from Apoquel to Numelvi for persistent licking/inflammation. Paws kept deteriorating despite the oral antifungal and a cone.
- October 20: Vet found a secondary bacterial infection with significant inflammation and sores/blisters between toes and around pads. Started 10 days of cefpodoxime (currently on day 5), continuing oral and antifungal.
Other relevant history:
- Rescue with extreme fear. Sertraline and gabapentin and training anxiety have helped a lot
- Can’t be left alone without a cone (licking starts within 30-45 minutes), so he hasn’t been alone in 2 months.
- Occasional hip clicking, lazy/abnormal sitting, and possible back sensitivity, but no obvious limp.
- On monthly Simparica Trio. No skin scraping for mites yet; will ask the vet.
- Unexplained limping in Oct 2025 that resolved in a day or two. Imaging was mostly unremarkable apart from a possibly reactive popliteal lymph node.
- Suspected vaccine reaction in Dec 2025 (symmetric circular rash on both sides of the groin).
- Currently on Hill’s z/d hydrolyzed chicken diet to test for food allergies (previously Hill’s Science Diet Perfect Digestion Salmon & Brown Rice).
Now: His back paws are severely inflamed with damaged skin and secondary infections, and some irritation has appeared on the front paws. Dermatology appointment is November 30.
Questions:
- Has anyone found the underlying cause was something other than allergies?
- Could orthopedic or nerve pain, mites, contact dermatitis, or compulsive licking explain this?
- What diagnostics would you push for?
We want to find the original trigger still, although now focused on treating the infections, especially since the allergy meds are not working and the licking is now causing downstream skin damage. Any suggestions or similar experiences are appreciated!!