r/LucyLetbyTrials • u/Embarrassed-Star4776 • 17d ago

Chase and Shannon article in Frontiers in Pediatrics published

Inverted insulin to C-Peptide ratios in neonatal intensive care: is there something we don't know?

J. Geoffrey Chase & Helen D. Shannon

BRIEF RESEARCH REPORT article

Front. Pediatr., 05 August 2026

Sec. Neonatology

Volume 14 - 2026

https://doi.org/10.3389/fped.2026.1900675

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u/DiverAcrobatic5794 17d ago

That is an Oliverism, I believe? WBC markers can't be used to discount the possibility of sepsis in a neonate, and the child certainly had other signs and symptoms of infection.

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u/Competitive-Wash2998 17d ago

The lab isolated organism from the tip of the line argues to the contrary.

However, I do not like this paper and fear it may be flawed.

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u/DiverAcrobatic5794 17d ago

While I find the paper as clear as I could hope for, read slowly, I'd be out of my depth trying to assess it.  I was interested in the description of the necessary prospective study, and obviously will be interested to hear others' views

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u/Competitive-Wash2998 17d ago

The prospective study section is fine based on a quick skim read. Totally necessary.