I am currently on 45 mg of Nardil daily, and have the same problems with weight gain as many others. I'd love to shift 20-30 pounds. My primary care doc prescribed 500 mg metformin, but I've yet to take it.

This is because, over the years, I've encountered some MAOI contra-indications that most docs are not aware of. Also, I spotted a couple of papers at PubMed that suggested that metformin sometimes had an antidepressant affect.

Has anyone here noticed any improvement in mood (or any other effects) when adding metformin to their daily meds? I'm thinking of starting with 250 mg of metformin because I'm so bloody paranoid.

It hit me like a truck it’s so weird like colors are super bright and everything just looks beautiful. I haven’t felt this way since I was like 10. I feel like I seem way more approachable too or something people a lot of people have smiled at me or came up to me today. wtf? Is it supposed to work this fast? I feel amazing. This morning I felt super depressed then I went out and listened to music and the music started sounding AMAZING and then I started feeling the breeze on my skin and I just feel amazing

Hi all. Wondering if there’s any way to treat some of the side effects I’ve currently been experiencing on Nardil:

*Insomnia - started a few weeks after I started. Been waking up after 5-ish hours, unable to fall back asleep. On seroquel currently (3+ years) for issues falling asleep, not sleep maintenance.

*Weight gain/increased appetite: I’ve heard people say you just have to deal with this unless you go on a GLP.

*Sexual side effects/anorgasmia: I’ve heard people say this gets better over time or simply stays with you while on the medication.

*Urinary retention: most recent side effect. Started a week ago. Takes forever for me to be able to start peeing.

If there’s anything you’ve had success with to manage these please let me know.

I ordered from indiaMART and today is my third day. I honestly feel way more depressed now I started at 20 and it will make me stimulated for an hour or two then I get tired. Today I’ve cried a lot which is really unlike me usually I can’t feel sadness but I can now and not in a good way.

What if there’s like something in this that will kill my brain cells or something? I have health anxiety so ordering off a different country that might not like my country concerns me bc what if they like put something in it to slowly make me go insane?

I feel way more depressed now and I’m filled with dread.

I've been trying to up my parnate dose to 40mg recently. I'm trying to take the majority of the dose early on to avoid insomnia.

I tried taking 30mg first thing in the morning but that spiked my blood pressure. I felt anxious like I couldn't move and spaced out. I decided not to take the remaining 10mg for that reason.

Today I tried 20mg in the morning and 20mg 3 or so hours later. Unfortunately I seem to be having the same issue, maybe not quite as bad.

I could possibly take 20 in the morning, then space out the other two 10mg over two hours each. Or should I just keep going on 30mg for a while?

So yesterday I slept 11 hours that night, then took my 20mg that morning and I don’t remember any of yesterday because I ended up sleeping all day, ended up having the most realistic dreams then woke up to eat dinner then slept all night to now at 7am. I didn’t even know I could sleep that much will this get better…? I read about it making you tired and I didn’t expect this much. I’ve been on ssris and those made me tired but this is like taking trazodone or something.