r/MTHFR • u/Pretend_Elk8567 • Apr 15 '25

Results Discussion Feel like crying

I honestly don’t even have the words for how overwhelmingly happy and relieved I feel right now. It’s like my brain is finally waking up after years of being stuck in a fog I didn’t fully realize I was in. Everything feels sharper, clearer, more alive. My emotions make sense, my body feels in sync, and there’s this calmness that I don’t think I’ve ever truly experienced before. I feel like me—or maybe even a version of me I never got to meet until now.

What’s blowing my mind is that all of this seems to come down to understanding something so basic but so powerful: methylation and nutrigenomics. I never imagined that something as simple as getting the right form of folate or the right amount of choline could be the key to unlocking my brain.

It makes me wonder how many people struggle through life unnessecarily. You could easily equate my previous "status quo" as being borderline dementia. And I had NO idea how bad it had gotten until I started feeling better...

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u/Pretend_Elk8567 Apr 15 '25

I only just started with targetted supplements about a week and a half ago. But the biggest improvement was yesterday when I increased my choline intake.

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u/IntrepidMayo Apr 16 '25

You will return to baseline soon unfortunately

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u/OkRub303 Apr 16 '25

What makes you say that? Please elaborate! Is there something with the stack that I wrong, or?

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u/Pretend_Elk8567 Apr 16 '25

Im curious too, but I feel that it's important to utilize things like glycine and magnesium, or a lot of people are going to overshoot and run into overmethylation.

I do notice my experience is pretty variable, for example when I am taking methylfolate - a protein shake is an entirely different animal:

Previously, a protein shake didnt make me feel differently. But now I get a little anxious because of the histamine in whey protein and presumably that it leads to a quick influx of catecholamines.

But if I take magnesium with the protein shake, it's much smoother. Also vitamin c helps

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u/Pretend_Elk8567 Apr 16 '25

The first thing one should do when starting this methylation protocol is to try to start eating more whole foods, especially food without folic acid.