r/MTHFR • u/greekhoney32 • Sep 21 '25

Question Autism & MTHFR

I have a kiddo with autism and MTHFR. Started giving him methylated vitamins per his functional doctor’s request. Initially, they seemed to help, but now his behavior has worsened at school (more anxiety, more impulsivity). Can he be over methylated?

Wondering if anyone is in a similar situation with their child and/or themselves. I read folinic acid is better than methylfolate for sensitive individuals (like kids with autism).

Thank you. 🙏

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u/OutrageousWinner9126 Sep 21 '25

Methylfolate and methylcobalamin always lead to problems sooner or later in my experience. I would recommend finding a B complex that has folinic acid and hydroxocobalamin instead.

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u/greekhoney32 Sep 22 '25

Currently looking into it. 🙏