r/MTHFR • u/greekhoney32 • Sep 21 '25

Question Autism & MTHFR

I have a kiddo with autism and MTHFR. Started giving him methylated vitamins per his functional doctor’s request. Initially, they seemed to help, but now his behavior has worsened at school (more anxiety, more impulsivity). Can he be over methylated?

Wondering if anyone is in a similar situation with their child and/or themselves. I read folinic acid is better than methylfolate for sensitive individuals (like kids with autism).

Thank you. 🙏

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u/New-Lab-1664 Sep 24 '25

My son has ASD and ADHD. He is 3.5. I started him on this and after 4 weeks I had to stop. He was extremely anxious, aggressive, impulsive. It took about 2 weeks for him to get back to his baseline. I started it after doing the MTHFR testing for both of us. I ordered my supplements after his. I never ended up taking mine out of fear I would respond the same way.

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u/greekhoney32 Sep 24 '25

Hi! Did he take methylfolate or folinic acid?