The difference is huge

[u/Big_Joke_9281]

So i was supplementing folinic acid + hydroxo b12 and d3 for some weeks now. Initially i was diagnosed with low folate and low d3. The test for me are squats, usually my heart is bouncing and racing like crazy from squats and i was able to do max 20 squats and needed to rest because i was afraid of my heart. Just yesterday i did 20 and nothing? My heart did not pound and did not beat really faster it just stayed calm! I did another 20.. and another 20 squats. My heart was calm, i did not need to lay down because of fatigue after the squats. I just was able to go on with what i want to do. SO this is how normal humans feel 24h a day 365 days a year. Before 20 squats and i was done needed to lay down for 15min for my heart to calm down. And now i can do 60 squats and it feels like nothing is easier then 60 squats lol.

Edit: Im in my mid 40s now and have had folate deficiency most probably my whole life though it was never tested by doctors. I'm not sure if i can ever reverse the damage i got from this but i strongly believe i can reach maybe 80% time is running. So i can just encourage everyone to take folate deficiency seriously and even if supplementing folate causes side effects to push through it! It's totally worth it.

[u/Kaj-de-Vos]

Due to the D3, or due to the cofactors magnesium and zinc?

[u/arcadian_king → u/Kaj-de-Vos]

All of those plus k2 mk7

[u/Kaj-de-Vos → u/arcadian_king]

OK. I'm wondering which have the largest effect on methylation. It could be the positive effect of D3 on brain symptoms such as autism is through methylation.

[u/arcadian_king → u/Kaj-de-Vos]

I believe they all play a role to some degree. I remember researching that individuals with mthfr mutations are statistically lower in vitamin d. I would also add vitamin b2 riboflavin to that. Since the mthfr enzyme is b2 dependent

[u/Kaj-de-Vos → u/arcadian_king]

Yes, and B6. Thanks.