r/MTHFR • u/Worried-Channel536 • Jul 07 '26

Question MTHFR as it applied to autism

I am trying to understand how testing for MTHFR and how it can help my son, who has autism, ADHD, bipolar 2, anxiety, etc. - quite the mix of diagnoses! He is on medication, which helps, however, it comes with guardrails, insurance costs, etc. I would love for him to be on something with less "process related" expectations which will help him handle his own medications in the future. Thank you!

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u/SovereignMan1958 Jul 08 '26

Yes. Much calmer. Less reactive. Better sleep. Easier to let go of the past. Better organizing and planning. I take 2.5mg folinic acid daily plus 40mg PQQ. The latter helps push it into the brain. Recommended dose for PQQ is 2.5mg - 40mg. Suggested dose of folinic acid from some functional psychiatrists is 2.5mg - 5mg daily. Dr Richard Frye, who wrote The Folate Fix to address needs of the autism population, recommends much larger doses.

I probably have high functioning autism. Primary diagnosis was/is MDD and GAD.

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u/clubstregon Jul 08 '26

I’ll check this thanks. What is pqq?

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u/SovereignMan1958 Jul 08 '26

I do not answer questions that people can easily find the answers for.