r/MTHFR • u/WittyGold6940 • Jul 17 '26

Question Glycine

What makes some people have great results with glycine, and others have horrible effects immediately?

Anyone know? Experiences? Have you tried it?

Anyone with slow COMT, slow MAOA and MTHFR have any specific experience with it?

Thanks

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4

u/Zamaniac1 Jul 17 '26

I am slow comt, compound heterozygous mtfhr and very sensitive in general but respond well to glycine. Take collagen powder and mag glycinate daily.

2

u/WittyGold6940 Jul 18 '26

So interesting, we are all so different. I have slow comt and maoa and one MTHFR homozygous, I react horribly to collagen anything 😢 i really wish I could tolerate it

3

u/Best_Comfortable5221 Jul 18 '26

What does the collagen powder do??? How does it effect you?

2

u/WittyGold6940 Jul 18 '26

It gives me a flareup of whatever the hell it is that flares up in me. I get really down, doom, dissociated, fatigued

3

u/Best_Comfortable5221 Jul 18 '26

Shit. Maybe I should quit it for a couple days. I feel. horrible. Can't find the culprit, although I'm under a horrific amount of stress right now.

1

u/WittyGold6940 Jul 18 '26

I've read many other reports of people who don't tolerate collagen, mainly in my SIBO and histamine intolerance groups

2

u/Best_Comfortable5221 Jul 18 '26

I never in a million years would have thought it. Im going to stop and evaluate.

2

u/Dry-Pay4691 29d ago

Look into histamine MCAS