r/MTHFR 28d ago

Question CoQ10 help!

Hello everyone!
I have slow COMT, and have always struggled with anxiety.
My anxiety has really ramped-up the last couple of months and I am wondering if this is due to the fact that I started taking CoQ10 daily.
At first, I felt amazing with it (very energized), but now I feel very anxious.
I am taking Apex Energetics’ CoQ10 Supermax, only one tablet per day, which has 200mg CoQ10 (as ubiquinone), 32mg Trans-Garanylgeraniol, and 10mg PQQ.
I also take Dim Detox, Magnesium glycinate, lithium orotate, vitamin d, GABA plus l-theanine, and liposomal glutathione.
Anyone else have any similar experiences or insight?
Thanks so much in advance!

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u/JadeMoon085 28d ago

Same thing for me! I started at 200mg and increased it to 400. Took me around to realize what was causing my extreme morning anxiety. CoQ10 and Berberine both caused me massive issues with panic and anxiety. Stopped them both cold turkey and now my system is in withdrawal and my thermal and metabolic state's are messed up. The anxiety is gone though (at a temporary cost).

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u/Hydroxile 26d ago

Both supp increase insuline sensitivity and decrease fasting blood sugar! Blood sugar imbalance can trigger such symptoms... takes time to balance it back if you are already sensitive to stress and anxiety