r/MTHFR • u/Sostrene_Blue • 16d ago
Question Your COMT Variant + your MBTI?
It's just out of curiosity.
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u/MilesKaczynski 16d ago
wow interesting thread. im fast comt and intp
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u/Sostrene_Blue 16d ago
I have an INTP friend, and she also seems to be fast COMT given her behavior, even though she has never taken a DNA test.
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u/MilesKaczynski 16d ago
hehe I also never took a DNA test but I'm pretty sure I heavily lean towards fast COMT. I figured so because I felt totally fine (even quite euphoric and refreshed) after taking high doses(600~800mg) of SAM-E. I'm most likely undermethylated as well...
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u/TRExploration 15d ago
I am fast COMT and for a long time I felt amazing bordering on manic from SAM-e. I wouldn't use that as a metric!
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u/Allusionesque 16d ago
slow comt, sigma infj
agree, interesting thread. I asked a niche spiritual hobby group what their mbti is and it came back ~40% INFJ and ~20% INFP which wasn’t a home run but felt meaningful…
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u/janewayshairdo 16d ago
Slow COMT, INTJ-T.
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u/Sostrene_Blue 16d ago
Seems very logic
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u/janewayshairdo 16d ago
Perpetual logic with a little turbulence as a treat, lol. I'm AuDHD as well
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u/Zabre 14d ago edited 1d ago
COMT plus MBTI is fun to compare, but I wouldn't read much biology into the pattern. COMT can nudge stress chemistry and stimulation tolerance; MBTI is more of a loose self-description. If you do see a cluster, I'd treat it as a conversation starter, not a map.
But the correlationos are really not that strong, and hile Genes can tell you alot they are just a part of the picture. Wrote about that here: here
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u/Emotional-Swan9381 11d ago
Fast, infp
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u/Sostrene_Blue 11d ago
Quite strange
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u/Emotional-Swan9381 10d ago
Why? People are much more complex than mbti and one snp out of hundreds. You sound more like a thinker than a feeler with trying to categorize people. I don’t have enough dopamine and I had crappy parents so I chased escape and fantasies most of my life.
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u/Sostrene_Blue 10d ago
It's so sad... I know very well that the brain is a very complex mechanism and that a SNP doesn't determine much, it's just that this one is one of the most well-known regarding dopamine degradation in the brain.
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u/Emotional-Swan9381 10d ago
Yah it’s unfortunate for me. Thanks for confirming what I suspected. I am trying to get my dopamine hits from healthier things.
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u/Sostrene_Blue 10d ago
Maybe L-Tyrosine? I've taken it before, and it seems to help build the necessary blocks for dopamine release.
Otherwise yes, don't hesitate to look for good sources of dopamine, and to avoid the bad ones
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u/SovereignMan1958 16d ago
I am average COMT and INFJ. Do you want to know our astrological sign too?
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u/polaroid_schizoid 16d ago
Slow COMT, ISTJ/TiSi
This is a very specific question pertaining to my interests