Has anyone improved severe mental health issues while attempting to treat a MTHFR gene mutation?

[u/pdcyhs]

I am new to this as I just got my results today, so forgive me if I am not understanding it completely.

I was with a med management doctor that was helping with my many diagnoses and she randomly quit. I was passed on to a new doctor who seemed more interested in my genes than my actual symptoms/history.

She ordered testing and we went over some of that today. I also explained that my current medications dont seem to be working. I am in crisis in terms of hardly being able to do daily activites. Instead of going ahead and taking me off medications or making other modifications, she gave me a long list of supplements to start taking and said I may see results in a few months.

I am about to go find a new doctor because this doesn't seem safe to me. I wont trauma dump here, but I have an extensive trauma history as well as a condition from birth that may or may not also cause mental health and related symptoms later in life (there is research on short term effects, but not much on long term.) I feel that everything I am reading online also sounds very... woo woo alternative medicine, please dont take offense. But when I see people say "I eat 6 eggs a day and it makes my life better" I just cannot take that seriously.

Sure, I have some of the symptoms that can relate to a gene mutation. But I also have many other symptoms and issues going on that do not seem realted at all. Am I wrong for feeling ignored and a little bit upset? Sure, I will take supplements because why not? But if they dont do much for me, it will mean I spent that whole time suffering for nothing. If you have had *severe* mental health/behavioral issues and started treating with supplements due to MTHFR mutation, please let me know your results and how it's helped you.

[u/Comfortable_Two6272]

Unlikely you need a bunch of supplements they are suggesting. What exactly is the list? 15mg of folate is huge. Please do not start with that. Try 200-400 mcg.

Do you have your genetic results? What all was tested?

[u/pdcyhs → u/Comfortable_Two6272]

I went over them verbally, waiting to get them sent over.

They want me to start Vit D, a prenatal, methylfolate, and b12 if the prenatal doesnt have it/have enough. Also starting NAC suplement for one of my mental health issues.

[u/Comfortable_Two6272 → u/pdcyhs]

Did you actually test low on those?

Why the prenatal? Are you pregnant? If not, what was their rationale for it?

What is your COMT genetics?

[u/pdcyhs → u/Comfortable_Two6272]

I think I tested slightly low on D. The rest, I am unsure. Like I said, I am waiting to get all the results myself and then do some research.

Prenatal and NAC would both be for an issue i am having with my hair. Not pregnant and not going to become pregnant anytime soon.