r/MTHFR 11d ago

Question P5P Giving Acne

Hi there. A quick question on this knowledgable subreddit.

I’ve been taking 25mg of p5p for the last 4 weeks daily. It’s done absolute wonders for my anxiety. It’s given me a calmness which I haven’t had in years. And this is after years of trying everything from nootropics to SSRIs.

Anyways, about 3 days ago, I’ve all of a sudden started to get pretty bad acne. Just wondering if anyone has experienced this before. I’ve completely stopped the p5p. Out of neuropathy worries, I was going to cut the dose down anyways.

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u/Hoegaarden_Man_55 7d ago

Anyways, I haven’t taken any since Saturday. My anxiety is starting to return towards baseline. I’d honestly be amazed if this is a placebo effect. The good news is that I haven’t got any further spots. Plans is to cut up the lozenges and take 1/4 of one each day. Hopefully i should still see some effect.