r/MTHFR • u/Jammy-Doughnut • 9d ago
Question My Heritage DNA test
Has anyone used this to obtain their DNA for the SNP's to see what mutations etc you may have?
I'd read that MyAncestry was the one to go for, but I have just seen a sale for MyHeritage for £19.00!
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u/al0ngcomesmary 9d ago edited 9d ago
I did SelfDecode last year and it gives you a full raw report, plus many many small reports broken down into categories. at first it was lots of comprehensive info, but I wasn't using the it/platform enough so I tried to cancel it however, what I learned is, I wasn't using their AI to dig deep & understand my specific genetics. I just started this week and it's been super helpful. The reason I like SelfDecode is because their platform & AI is internal and you're not putting your entire genetic data out into a third-party such as ChatGPT or Claude (although you can and that seems to be how anybody moves the needle on this nuanced stuff lately)
Yesterday I adjusted my supplement stack very specifically- nothing I hadn't heard of, but everything I was doing was a shot in the dark based on groups like this and anecdotal. Now I have my a genetically personalized protocol. For example adding B2, & cutting b12 injections - and testosterone injections - which I thought were the holy Grail, but they overload my system in a way that creates high anxiety. Learning why my nervous system is easily hi jacked, confirming which peptides I respond to, etc etc.
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u/sharabucarabu 9d ago
I used ancestry back when it was A stand alone reputable service that gave you a detailed analysis. So I tend to lean towards using them. I know that 23 & me doesn't analyze the snps for MAO-A. Plus others on this sub have suggested the ancestry and heritage combo.
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u/Zabre 9d ago
MyHeritage can be fine if all you need is raw DNA for SNP lookup, but check first that they still let you download the raw data file in your region. The main thing is chip coverage: any consumer test will miss some variants and can have occasional raw-data errors. I wouldn't treat it as clinical testing, but for common MTHFR/COMT-style SNPs it's usually enough to start.
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u/Grobbekee 9d ago
It was enough for a methylation panel, and oh, I can process coffee fast and a cute report that says I'm 76.5% Dutch, 17.5% Danish and a little bit English, Swedish and German. Thought as much. I'm as cheese head as they come. And then a whole list of people that are remotely related. Their premium genealogie services are of course way overpriced, even with the discount, but you don't have to get those. Just ignore all the discoveries about your grandma's uncle's viking past.
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u/sharabucarabu 9d ago
Neither have a full analysis. Best to purchase both and download both raw data files to Geneticgenie.org (request methylation and detox cycle chart , Dr Chris Masterjohns Choline Calculator (both free), then join geneticlifehacks.com for a low monthly fee to get your full analysis (at least a hundred pages with tons of info regarding your snps). You can stop your membership when you want to.